Recommendations from Gynaecological (GYN) GEC-ESTRO Working Group (IV): Basic principles and parameters for MR imaging within the frame of image based adaptive cervix cancer brachytherapy.

Recommendations from Gynaecological (GYN) GEC-ESTRO Working Group (IV): Basic principles and parameters for MR imaging within the frame of image based adaptive cervix cancer brachytherapy.
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DOI:
10.1016/j.radonc.2011.12.024
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发表时间:
2012-04
期刊:
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology
影响因子:
--
通讯作者:
Pötter R
Pötter R
中科院分区:
其他
文献类型:
--
作者:
Dimopoulos JC;Petrow P;Tanderup K;Petric P;Berger D;Kirisits C;Pedersen EM;van Limbergen E;Haie-Meder C;Pötter R

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GYN GEC-ESTRO工作组发布了三部分建议,并强调了MRI在成功实施基于3D图像的宫颈癌近距离放射治疗(BT)方面的关键作用。MRI作为一种成像手段的主要优势是其优越的软组织成像质量。为了充分发挥MRI的潜力,使放射肿瘤学家能够更好地为BT应用技术做出适当的选择,并准确地确定靶区和危险器官,必须满足某些MR成像标准。技术要求、患者准备以及图像采集协议必须针对基于3D图像的BT的需求进行量身定做。本建议着重于基于3D图像的BT的MR成像的一般原理。从不同机构(IGR、维也纳大学、鲁汶大学、奥胡斯大学和卢布尔雅那大学)的临床经验中开发并逐步验证了方法和参数,并在专家会议、轮廓绘制研讨会以及临床和观察者间研究中成功应用。用一台MR成像仪在放疗前(“RT-MRI前检查”)和BT时(“BT MRI检查”)进行盆腔MRI扫描是有用的。低场和高场成像器以及开放和闭合磁铁配置都符合基于3D图像的宫颈癌BT的要求。多平面(横断面、矢状位、冠状位和斜位)盆腔表面线圈T2加权图像被认为是显示肿瘤和关键器官的黄金标准。使用互补的MRI序列(例如,对比增强的T1加权或3D各向同性MRI序列)是可选的。患者的准备工作必须适应BT介入和磁共振成像的需要。建议在专用的DICOM查看器工作站上可视化和解释MR图像,这也应该有助于轮廓绘制过程。成像参数和BT设备的选择是在考虑了成像和敷贴器重建之间的相互作用以及成像、几何和剂量计算之间的相互作用之后做出的。在前瞻性的临床背景下,为了实施基于3D图像的宫颈癌近距离放射治疗并充分利用其潜力,成功地满足GYN GEC-ESTRO工作组目前建议的MR成像标准是至关重要的。
The GYN GEC-ESTRO working group issued three parts of recommendations and highlighted the pivotal role of MRI for the successful implementation of 3D image-based cervical cancer brachytherapy (BT). The main advantage of MRI as an imaging modality is its superior soft tissue depiction quality. To exploit the full potential of MRI for the better ability of the radiation oncologist to make the appropriate choice for the BT application technique and to accurately define the target volumes and the organs at risk, certain MR imaging criteria have to be fulfilled. Technical requirements, patient preparation, as well as image acquisition protocols have to be tailored to the needs of 3D image-based BT. The present recommendation is focused on the general principles of MR imaging for 3D image-based BT. Methods and parameters have been developed and progressively validated from clinical experience from different institutions (IGR, Universities of Vienna, Leuven, Aarhus and Ljubljana) and successfully applied during expert meetings, contouring workshops, as well as within clinical and interobserver studies. It is useful to perform pelvic MRI scanning prior to radiotherapy (“Pre-RT-MRI examination”) and at the time of BT (“BT MRI examination”) with one MR imager. Both low and high-field imagers, as well as both open and close magnet configurations conform to the requirements of 3D image-based cervical cancer BT. Multiplanar (transversal, sagittal, coronal and oblique image orientation) T2-weighted images obtained with pelvic surface coils are considered as the golden standard for visualisation of the tumour and the critical organs. The use of complementary MRI sequences (e.g. contrast-enhanced T1-weighted or 3D isotropic MRI sequences) is optional. Patient preparation has to be adapted to the needs of BT intervention and MR imaging. It is recommended to visualise and interpret the MR images on dedicated DICOM-viewer workstations, which should also assist the contouring procedure. Choice of imaging parameters and BT equipment is made after taking into account aspects of interaction between imaging and applicator reconstruction, as well as those between imaging, geometry and dose calculation. In a prospective clinical context, to implement 3D image-based cervical cancer brachytherapy and to take advantage of its full potential, it is essential to successfully meet the MR imaging criteria described in the present recommendations of the GYN GEC-ESTRO working group.
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