Prevalence of inappropriate use behaviors of antibiotics and related factors among chinese antibiotic users: an online cross-sectional survey.
Prevalence of inappropriate use behaviors of antibiotics and related factors among chinese antibiotic users: an online cross-sectional survey.
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中国抗生素使用者抗生素不当使用行为及相关因素的流行情况：在线横断面调查
DOI：
10.1186/s12879-022-07671-1
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发表时间：
2022-08-13
影响因子：
3.7
通讯作者：
Li, Hui
中科院分区：
文献类型：
--
作者：
Yin, Xiaoxv;Gong, Yanhong;Sun, Na;Li, Dandan;Wu, Jianxiong;Wang, Jing;Qiu, Lei;Li, Hui
不当使用抗生素可能对个人和社区产生深远的负面影响。本研究旨在了解我国抗生素使用者抗生素不当使用行为的发生率，并探讨其相关因素。横断面调查于2018年7月1日至2018年9月30日进行。通过在线调查平台（questionnaire Star, https://www.wjx.cn）广泛发放结构化问卷，收集中国受访者的人口学和社会学特征、抗生素使用及相关知识等数据。主要结局包括抗生素自行用药（SMA）、抗生素自行储存（SSA）和抗生素治疗不依从性（NAAT）。采用Logistic回归分析上述抗生素不正当使用行为的相关因素。在15526名参与者中，37.1%的人报告过去6个月有SMA， 67.9%的人报告过去6个月有SSA， 48.3%、15.2%、25.5%和78.0%的受访者表示他们错过了抗生素，增加了抗生素剂量，减少了抗生素剂量，症状消失后停用了抗生素。总体而言，53.3%的人在此期间报告了NAAT。在调整其他变量后，多因素logistic回归分析显示，年龄在30-44岁、文化程度较高、自我健康状况较差或抗生素知识水平较低的人群更容易出现SMA、SSA和NAAT的不当使用行为（P < 0.05）。SMA、SSA和NAAT在中国的患病率很高。迫切需要制定公众合理使用抗生素的全国性行动计划，包括全国媒体宣传、线上线下健康教育和全科医生用药指导。自行用药、自行储存、不遵医嘱是抗生素不适当使用行为的重要表现。本研究结果显示，我国抗生素使用者中抗生素不正当使用行为的发生率在37.1% ~ 67.9%之间。中国迫切需要制定合理使用抗生素的全国性行动计划。
Inappropriate use of antibiotics could have a profound negative impact on individual and community. This study aimed to assess the prevalence of inappropriate use behaviors of antibiotics in Chinese antibiotic users and explored their related factors. A cross-sectional survey was conducted from July 1, 2018 to September 30, 2018. A structured questionnaire was widely distributed on the online survey platform (Questionnaire Star, https://www.wjx.cn) and was used to collect data from respondents in China on demographic and sociological characteristics, antibiotic use and related knowledge. Main outcomes included self-medication with antibiotics (SMA), self-storage with antibiotics (SSA), and non-adherence to antibiotic treatment (NAAT). Logistic regression was used to identify the related factors of above inappropriate use behaviors of antibiotics. Of the 15,526 participants, 37.1% reported SMA in the past 6 months, 67.9% reported SSA in the past 6 months, and 48.3%, 15.2%, 25.5% and 78.0% of respondents said that they had missed antibiotics, increased antibiotic dosage, decreased antibiotic dosage, and discontinued antibiotics once symptoms disappear, respectively. Overall, 53.3% reported NAAT during this period. After adjusting for other variables, multivariate logistic regression analyses showed that those aged 30–44 years old, with higher levels of education, poorer status of self-perceived health, or lower levels of antibiotic knowledge were more likely to have these inappropriate use behaviors of SMA, SSA, and NAAT (P < 0.05). The prevalence of SMA, SSA, and NAAT is high in China. Developing a nationwide action plan for the rational use of antibiotics among publics, including national media publicity, online and offline health education, and medication guidance from general practitioners, is urgently needed. Self-medication with antibiotics, self-storage with antibiotics, and non-adherence to antibiotic treatment are important performances of inappropriate use behaviors of antibiotics. The results of this study showed that the prevalence of inappropriate use behaviors of antibiotics among Chinese antibiotic users were between 37.1% and 67.9%. A nationwide action plan for rational use of antibiotics is urgently needed in China.
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DOI：
10.1016/j.ijantimicag.2005.02.009
发表时间：
2005-05-01
影响因子：
10.8
作者：
Mitsi, G;Jelastopulu, E;Gogos, C
通讯作者：
Gogos, C
影响因子：
3.4
作者：
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Mistretta, A.
DOI：
10.1590/s0120-41572014000400011
发表时间：
2014-12-01
期刊：
Biomédica
影响因子：
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作者：
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通讯作者：
Ruiz-Villa, Joaquín Octavio
影响因子：
2.4
作者：
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Vlcek, Jiri
影响因子：
4.5
作者：
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Obua C