Self-assembled hybrid nanoparticles for targeted co-delivery of two drugs into cancer cells.
Self-assembled hybrid nanoparticles for targeted co-delivery of two drugs into cancer cells.
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DOI:
10.1039/c3cc49003c
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发表时间:
2014-03-21
期刊:
影响因子:
--
通讯作者:
Tan W
中科院分区:
文献类型:
--
作者:
Huang F;You M;Chen T;Zhu G;Liang H;Tan W
A therapeutic aptamer-lipid-poly(lactide-co-glycolic acid) hybrid nanoparticle-based drug delivery system was prepared and characterized. The hybrid can co-deliver two different drugs with distinct solubility characteristics and different anticancer mechanisms to target cancer cells with high specificity and efficiency.
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