Update on Imaging-Based Measurement of Bone Mineral Density and Quality.

Update on Imaging-Based Measurement of Bone Mineral Density and Quality.
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DOI:
10.1007/s11926-020-00892-w
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发表时间:
2020-04-09
影响因子:
5
通讯作者:
Kazakia G
Kazakia G
中科院分区:
医学2区
文献类型:
--
作者:
Link TM;Kazakia G

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Patients with inflammatory arthropathies have a high rate of fragility fractures. Diagnostic assessment and monitoring of bone density and quality are therefore critically important. Here, we review standard and advanced techniques to measure bone density and quality, specifically focusing on patients with inflammatory arthropathies. Current standard procedures are dual-energy X-ray absorptiometry (DXA) and quantitative computed tomography (QCT). DXA-based newer methods include trabecular bone score (TBS) and vertebral fracture assessment (VFA). More advanced imaging methods to measure bone quality include high-resolution peripheral quantitative computed tomography (HR-pQCT) as well as multi-detector CT (MD-CT) and magnetic resonance imaging (MRI). Quantitative ultrasound has shown promise but is not standard to assess bone fragility. While there are limitations, DXA remains the standard technique to measure density in patients with rheumatological disorders. Newer modalities to measure bone quality may allow better characterization of bone fragility but currently are not standard of care procedures.
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