Corticospinal Tract Lesion Load Originating From Both Ventral Premotor and Primary Motor Cortices Are Associated With Post-stroke Motor Severity.
Corticospinal Tract Lesion Load Originating From Both Ventral Premotor and Primary Motor Cortices Are Associated With Post-stroke Motor Severity.
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源自腹侧前运动皮质和原发性运动皮质的皮质脊髓束病变负荷与中风后运动的严重程度有关。
DOI：
10.1177/15459683211068441
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发表时间：
2022-03
影响因子：
4.2
通讯作者：
Liew SL
中科院分区：
文献类型：
--
作者：
Ito KL;Kim B;Liu J;Soekadar SR;Winstein C;Yu C;Cramer SC;Schweighofer N;Liew SL
皮质脊髓束损伤负荷（CST- ll）是衡量脑卒中损伤与CST之间重叠程度的指标，是脑卒中后运动预后的最强预测指标之一。CST- ll通常是通过使用源自初级运动皮层（M1）的CST的概率图来计算的。然而，高阶运动区域也有有助于CST和运动控制的投影。在这项回顾性研究中，我们研究了是否评估来自其他运动来源的CST-LL与中风后运动严重程度的关系比仅来自M1的CST-LL更强。我们发现腹侧运动前皮层（PMv）和M1的损伤负荷与Fugl-Meyer评估截止分数指标的卒中运动严重程度的相关性比单独M1的CST-LL更强，这表明高阶运动区域增加了运动损伤的临床相关性。
Lesion load of the corticospinal tract (CST-LL), a measure of overlap between a stroke lesion and the CST, is one of the strongest predictors of motor outcomes following stroke. CST-LL is typically calculated by using a probabilistic map of the CST originating from the primary motor cortex (M1). However, higher-order motor areas also have projections that contribute to the CST and motor control. In this retrospective study, we examined whether evaluating CST-LL from additional motor origins is more strongly associated with post-stroke motor severity than using CST-LL originating from M1 only. We found that lesion load to both the ventral premotor (PMv) cortex and M1 were more strongly related to stroke motor severity indexed by Fugl-Meyer Assessment cut-off scores than CST-LL of M1 alone, suggesting that higher-order motor regions add clinical relevance to motor impairment.
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影响因子：
4.2
作者：
Kantak SS;Stinear JW;Buch ER;Cohen LG
通讯作者：
Cohen LG
DOI：
10.1016/j.apmr.2013.03.007
发表时间：
2013-08-01
影响因子：
4.3
作者：
Woodbury, Michelle L.;Velozo, Craig A.;Duncan, Pamela W.
通讯作者：
Duncan, Pamela W.
影响因子：
3.7
作者：
Archer, Derek B.;Vaillancourt, David E.;Coombes, Stephen A.
通讯作者：
Coombes, Stephen A.
影响因子：
4.3
作者：
Woytowicz EJ;Rietschel JC;Goodman RN;Conroy SS;Sorkin JD;Whitall J;McCombe Waller S
通讯作者：
McCombe Waller S
影响因子：
8.3
作者：
Riley JD;Le V;Der-Yeghiaian L;See J;Newton JM;Ward NS;Cramer SC
通讯作者：
Cramer SC