Distribution of interstitial retinol-binding protein (IRBP) in the vertebrates.
Distribution of interstitial retinol-binding protein (IRBP) in the vertebrates.
复制标题
间质视黄醇结合蛋白（IRBP）在脊椎动物中的分布。
DOI：
10.1002/jez.1402390305
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发表时间：
1986
期刊：
影响因子：
--
通讯作者：
Fong,SL
中科院分区：
文献类型：
--
作者：
Bridges,CD;Liou,GI;Alvarez,RA;Landers,RA;LandryJr,AM;Fong,SL
Immunoblots of interphotoreceptor matrix preparations from 20 species belonging to six vertebrate classes were probed with antibodies against bovine interstitial retinol‐binding protein (b‐IRBP). Each preparation displayed an immunoreactive protein band. In the Osteichthyes, the apparent Mrof this band was 67,600 ± 2,700 (x̄ ± SD, n = 8). In two of the Osteichthyes, the band was resolved into a closely spaced doublet. Including previously published data for five mammals and one amphibian, species from the other classes (Chondrichthyes, one species; Amphibia, four species; Reptilia, one species; Aves, one species; Mammalia, nine species) had IRBPs with Mrthat averaged 2.0 times that of the Osteichthyes, namely 134,200 ± 8,600 (x̄ ± SD, n = 17). Frog IRBP was very similar to mammalian IRBP in terms of its immunohistochemical distribution (determined with rabbit anti‐frog IRBP antibodies), its molecular weight (sodium dodecyl sulfate polyacrylamide gel electrophoresis and gel‐filtration chromatography), retinol‐ and concanavalin A‐binding ability, and because it was synthesized and secreted in vitro by the isolated retina but not by the pigmented layers of eye. Goldfish IRBP apparently binds exogenous (3H)‐retinol but does not bind concanavalin A and has about half the Mrof frog IRBP. The occurrence of IRBP‐like proteins crossreacting with anti b‐IRBP antibodies in the interphotoreceptor matrix of all six major vertebrate classes is consistent with the hypothesis that IRBP is an important element in the vertebrate visual cycle.
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凝集素作为视杆细胞和视锥细胞中糖蛋白和糖脂寡糖的探针
影响因子：
4.2
作者：
C. Bridges;S. Fong
通讯作者：
S. Fong
牛神经视网膜合成和分泌的视黄醇结合糖蛋白的纯化和表征。
DOI：
--
发表时间：
1984
期刊：
The Journal of biological chemistry
影响因子：
--
作者：
Fong,SL;Liou,GI;Landers,RA;Alvarez,RA;Bridges,CD
通讯作者：
Bridges,CD
视网膜感光器间空间中存在可溶性感光器间视黄醇结合蛋白（IRBP）
影响因子：
5.6
作者：
B. A. Pfeffer;B. Wiggert;L. Lee;B. Zonnenberg;D. Newsome;G. Chader
通讯作者：
G. Chader
牛光感受器间视黄醇结合蛋白的分子特性。
DOI：
--
发表时间：
1985
期刊：
The Journal of biological chemistry
影响因子：
--
作者：
Adler,AJ;Evans,CD;Stafford3rd,WF
通讯作者：
Stafford3rd,WF
影响因子：
2.9
作者：
REDMOND, TM;WIGGERT, B;CHADER, GJ
通讯作者：
CHADER, GJ