Modelling the response of whispering-gallery-mode optical resonators for biosensing applications

Modelling the response of whispering-gallery-mode optical resonators for biosensing applications
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针对生物传感应用的回音壁模式光学谐振器的响应建模

DOI:
10.1117/12.808790
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发表时间:
2009
期刊:
--
影响因子:
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通讯作者:
Langbein W
Langbein W
中科院分区:
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文献类型:
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作者:
Langbein W

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我们提出了对生物传感应用的窃窃廊模式响应的理论分析,在微柱中进行了数值研究,在微球中进行了半分析。计算了单个和多个粒子的效应,模拟了附着在微谐振器表面的不同尺寸和极化度的生物分析物。除了低语走廊模式的频移,我们还发现,由于粒子附着和/或靠近平面耦合器,也会出现宽度和分裂(从提升的旋转对称性)。对于单个分析物,粒径和折射率都可以通过拓宽和移动来确定,为新的生物传感模式打开了前景。
We present a theoretical analysis of the response of whispering gallery modes for biosensing applications, studied numerically in microcylinders and semi-analytically in microspheres. The effect of single and multiple particles is calculated, simulating biological analytes of different sizes and polarizabilities attached to the microresonator surface. Besides whispering-gallery-mode frequency shifts, we find that also broadenings and splittings (from lifted rotational symmetry) appear due to particles attachment and/or the vicinity to a planar coupler. For a single analyte, both particle size and refractive index can be determined from the broadening and shift, opening the perspective to a new biosensing modality.
DOI: 10.1063/1.2795332
发表时间: 2007-10-01
影响因子: 4
作者:
Lutti, Julie;Langbein, Wolfgang;Borri, Paola
通讯作者: Borri, Paola
DOI: 10.1109/16.141223
发表时间: 1992-07-01
影响因子: 3.1
作者:
YUAN, CM
通讯作者: YUAN, CM
DOI: 10.1364/josab.25.001312
发表时间: 2008-08-01
影响因子: 1.9
作者:
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通讯作者: Langbein, W.