exTREEmaTIME: a method for incorporating uncertainty into divergence time estimates.
exTREEmaTIME: a method for incorporating uncertainty into divergence time estimates.
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DOI:
10.1242/bio.059181
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发表时间:
2022-02-15
期刊:
影响因子:
2.4
通讯作者:
Scotland RW
中科院分区:
文献类型:
--
作者:
Carruthers T;Scotland RW
We present a method of divergence time estimation (exTREEmaTIME) that aims to effectively account for uncertainty in divergence time estimates. The method requires a minimal set of assumptions, and, based on these assumptions, estimates the oldest possible divergence times and youngest possible divergence times that are consistent with the assumptions. We use a series of simulations and empirical analyses to illustrate that exTREEmaTIME is effective at representing uncertainty. We then describe how exTREEmaTIME can act as a basis to determine the implications of the more stringent assumptions that are incorporated into other methods of divergence time estimation that produce more precise estimates. This is critically important given that many of the assumptions that are incorporated into these methods are highly complex, difficult to justify biologically, and as such can lead to estimates that are highly inaccurate. Summary: We present a method for estimating evolutionary timescales that makes minimal assumptions and accurately reflects uncertainty. This enables evolutionary researchers to test hypotheses in contexts where uncertainty is adequately accounted for, and to determine the implications of the more stringent assumptions that underpin other methods.
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DOI:
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发表时间:
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发表时间:
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影响因子:
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作者:
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通讯作者:
Scotland, Robert W.