Zika among international travellers presenting to GeoSentinel sites, 2012-2019: implications for clinical practice.
Zika among international travellers presenting to GeoSentinel sites, 2012-2019: implications for clinical practice.
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DOI：
10.1093/jtm/taaa061
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发表时间：
2020-07-14
影响因子：
25.7
通讯作者：
Wilder-Smith A
中科院分区：
文献类型：
--
作者：
Angelo KM;Stoney RJ;Brun-Cottan G;Leder K;Grobusch MP;Hochberg N;Kuhn S;Bottieau E;Schlagenhauf P;Chen L;Hynes NA;Perez CP;Mockenhaupt FP;Molina I;Crespillo-Andújar C;Malvy D;Caumes E;Plourde P;Shaw M;McCarthy AE;Piper-Jenks N;Connor BA;Hamer DH;Wilder-Smith A
国际旅行者促成了寨卡病毒(ZIKV)及其哨兵身份在全球的快速传播。我们描述了在GeSentinel网站看到的国际旅行者中的寨卡病毒感染情况，重点是在美洲和加勒比地区获得的寨卡病毒，描述了暴露国家和旅行者的特征，并按地点评估寨卡病毒诊断检测。2012年1月至2019年12月期间向GeoSentinel报告的与国际旅行有关的确诊或可能ZIKV诊断的记录以及记录的发病日期被包括在内，以显示一段时间内报告的病例。描述性分析包括2016年3月至2019年12月期间美洲或加勒比地区的风险敞口区域的记录。进行了一项调查，以评估在GeoSentinel站点进行ZIKV诊断测试的可用性、可及性和利用率。GeoSentinel网站报告了从2012年到2019年的525例寨卡病毒病例。2012至2014年间，报告了8例病例，全部是在亚洲或大洋洲获得的。2014年后，大多数病例在美洲或加勒比地区获得，2018-19年ZIKV病例出现较大下降。2016年3月至2019年12月，423名患者在美洲或加勒比地区感染ZIKV，这些地区的报告高峰出现在2016年[330例(78%)]。中位年龄为36岁(范围：3-92岁)；63%为女性。接触最频繁的地区是加勒比海(60%)。13名旅行者在旅行期间或旅行后怀孕；其中一人感染了性传播寨卡病毒。有一例胎儿畸形，两名旅行者患有格林-巴利综合征。GeoSentinel网站报告了有效诊断寨卡病毒的各种挑战。对于从有寨卡病毒传播风险的地区返回的旅行者来说，寨卡病毒仍应是一个考虑因素。旅行者应该与他们的医疗保健提供者讨论他们的旅行计划，以确保采取ZIKV预防措施。
International travellers contribute to the rapid spread of Zika virus (ZIKV) and its sentinel identification globally. We describe ZIKV infections among international travellers seen at GeoSentinel sites with a focus on ZIKV acquired in the Americas and the Caribbean, describe countries of exposure and traveller characteristics, and assess ZIKV diagnostic testing by site. Records with an international travel-related diagnosis of confirmed or probable ZIKV from January 2012 through December 2019 reported to GeoSentinel with a recorded illness onset date were included to show reported cases over time. Records from March 2016 through December 2019 with an exposure region of the Americas or the Caribbean were included in the descriptive analysis. A survey was conducted to assess the availability, accessibility and utilization of ZIKV diagnostic tests at GeoSentinel sites. GeoSentinel sites reported 525 ZIKV cases from 2012 through 2019. Between 2012 and 2014, eight cases were reported, and all were acquired in Asia or Oceania. After 2014, most cases were acquired in the Americas or the Caribbean, a large decline in ZIKV cases occurred in 2018–19. Between March 2016 and December 2019, 423 patients acquired ZIKV in the Americas or the Caribbean, peak reporting to these regions occurred in 2016 [330 cases (78%)]. The median age was 36 years (range: 3–92); 63% were female. The most frequent region of exposure was the Caribbean (60%). Thirteen travellers were pregnant during or after travel; one had a sexually acquired ZIKV infection. There was one case of fetal anomaly and two travellers with Guillain-Barré syndrome. GeoSentinel sites reported various challenges to diagnose ZIKV effectively. ZIKV should remain a consideration for travellers returning from areas with risk of ZIKV transmission. Travellers should discuss their travel plans with their healthcare providers to ensure ZIKV prevention measures are taken.
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影响因子：
3.3
作者：
Kwong, Jason C.;Druce, Julian D.;Leder, Karin
通讯作者：
Leder, Karin
影响因子：
120.7
作者：
Honein, Margaret A.;Dawson, April L.;Jamieson, Denise J.
通讯作者：
Jamieson, Denise J.
影响因子：
4.2
作者：
Paixao, Enny S.;Leong, Wei-Yee;Wilder-Smith, Annelies
通讯作者：
Wilder-Smith, Annelies
影响因子：
11.8
作者：
Lammert S;Walker AT;Erskine S;Rao SR;Esposito DH;Ryan ET;Robbins GK;LaRocque RC
通讯作者：
LaRocque RC
影响因子：
39.2
作者：
Hamer, Davidson H.;Barbre, Kira A.;Esposito, Douglas H.
通讯作者：
Esposito, Douglas H.