Gender differences in factors associated with delirium severity in older adults with dementia.

Gender differences in factors associated with delirium severity in older adults with dementia.
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DOI:
10.1016/j.apnu.2014.01.004
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发表时间:
2014-06
影响因子:
2.3
通讯作者:
Valenzuela, Michael
Valenzuela, Michael
中科院分区:
医学4区
文献类型:
--
作者:
Kolanowski, Ann M.;Hill, Nikki L.;Kurum, Esra;Fick, Donna M.;Yevchak, Andrea M.;Mulhall, Paula;Clare, Linda;Valenzuela, Michael

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本描述性相关性研究的目的是探讨老年人痴呆严重程度、年龄、APOE状态、认知储备和合并症(两个潜在的可修改因素)与谵妄严重程度之间关系的潜在性别差异。分析中使用了正在进行的临床试验的基线数据和泊松回归程序。参与者是148名患有痴呆和谵妄的老年人,他们接受了急性期后护理。在女性中,谵妄的严重程度与痴呆的严重程度相关(p= 0.002),合并症的影响缓和(p=0.03)。在男性中,教育程度与谵妄严重程度轻微相关(p=0.06)。研究的影响进行了讨论。
The purpose of this descriptive correlational study was to explore potential gender differences in the relationship of dementia severity, age, APOE status, cognitive reserve and co-morbidity, (two potentially modifiable factors), to delirium severity in older adults. Baseline data from an ongoing clinical trial and a Poisson regression procedure were used in the analyses. Participants were 148 elderly individuals with dementia and delirium admitted to post-acute care. In women, delirium severity was related to dementia severity (p= 0.002) and co-morbidity moderated that effect (p=0.03). In men, education was marginally associated with delirium severity (p=0.06). Implications for research are discussed.
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