Methadone maintenance therapy service components linked to improvements in HIV care cascade outcomes: A systematic review of trials and observational studies.
Methadone maintenance therapy service components linked to improvements in HIV care cascade outcomes: A systematic review of trials and observational studies.
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DOI：
10.1016/j.drugalcdep.2020.108342
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发表时间：
2021-01-01
影响因子：
4.2
通讯作者：
Richardson L
中科院分区：
文献类型：
--
作者：
Mohd Salleh NA;Voon P;Karamouzian M;Milloy MJ;Richardson L
参与美沙酮维持治疗（MMT）和艾滋病毒治疗结果之间的有益联系已被广泛描述。然而，吸毒者（PWUD）继续经历不理想的艾滋病毒治疗结果。在这项系统性综述中，我们试图确定MMT服务提供的组成部分，这些组成部分与整个艾滋病毒护理级联中艾滋病毒护理结果的改善相关。我们在在线数据库中搜索同行评议的研究。要符合纳入本综述的条件，研究必须涉及参与MMT的PWUD人群或亚群;报告HIV检测的吸收改善，ART暴露或HIV-1 RNA血浆病毒载量抑制;提供MMT服务的详细信息;并在2006年1月1日至2018年12月31日期间以英文发表。在识别的5594项记录中，有22项研究符合本系统综述的条件。将研究中描述的与HIV护理级联结局相关的MMT服务的组成部分分为三类护理模式：1）具有足够剂量的标准MMT护理，2）标准MMT护理以及额外的医疗组成部分，3）标准MMT护理，额外的医疗组成部分以及信息或工具性社会支持。确定的少数研究反映了缺乏证据的作用，社会支持，以增加MMT的好处PWUD谁是艾滋病毒感染者。需要进一步的研究来评估MMT护理提供中的医疗和社会服务组成部分在推进PWUD沿着HIV护理级联中的作用。
The beneficial links between engagement in methadone maintenance therapy (MMT) and HIV treatment outcomes have been extensively described. Nevertheless, people who use drugs (PWUD) continue to experience suboptimal HIV treatment outcomes. In this systematic review, we sought to identify components of MMT service provision that are associated with improvements in HIV care outcomes across the HIV care cascade. We searched for peer-reviewed studies in online databases. To be eligible for inclusion in this review, studies must have involved a population or sub-population of PWUD engaged in MMT; report improved uptake of HIV testing, exposure to ART, or HIV-1 RNA plasma viral load suppression; provide details on MMT services; and be published in English between 1 January 2006 until 31 December 2018. Out of the 5594 identified records, 22 studies were eligible for this systematic review. Components of MMT services associated with HIV care cascade outcomes described in the studies were classified in three categories of care models: 1) standard MMT care with adequate doses, 2) standard MMT care and alongside additional medical component(s), and 3) standard MMT care, additional medical component(s) as well as informational or instrumental social support. The few studies identified reflect a scarcity of evidence on the role of social support to increase the benefits of MMT for PWUD who are living with HIV. Further research is needed to assess the role of medical and social service components in MMT care delivery in advancing PWUD along the HIV care cascade.
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影响因子：
3.7
作者：
Carrieri PM;Michel L;Lions C;Cohen J;Vray M;Mora M;Marcellin F;Spire B;Morel A;Roux P;Methaville Study Group
通讯作者：
Methaville Study Group
DOI：
10.1080/09540121.2017.1394965
发表时间：
2018-01-01
影响因子：
1.7
作者：
Ayon, Sylvia;Ndimbii, James;Mburu, Gitau
通讯作者：
Mburu, Gitau
影响因子：
2.2
作者：
Conyers, Liza;Boomer, K. B.
通讯作者：
Boomer, K. B.
影响因子：
4.2
作者：
Berg, Karina M.;Litwin, Alain;Li, Xuan;Heo, Moonseong;Arnsten, Julia H.
通讯作者：
Arnsten, Julia H.
影响因子：
1.4
作者：
George S;Garth B;Wohl AR;Galvan FH;Garland W;Myers HF
通讯作者：
Myers HF