Secondary analyses to test the impact on inequalities and uptake of the schools-based human papillomavirus (HPV) vaccination programme by stage of implementation of a new consent policy in the south-west of England.

Secondary analyses to test the impact on inequalities and uptake of the schools-based human papillomavirus (HPV) vaccination programme by stage of implementation of a new consent policy in the south-west of England.
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DOI:
10.1136/bmjopen-2020-044980
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发表时间:
2021-07-07
期刊:
影响因子:
2.9
通讯作者:
Audrey S
Audrey S
中科院分区:
医学3区
文献类型:
--
作者:
Fisher H;Evans K;Reynolds R;Yates J;Roderick M;Ferrie J;Macleod J;Hickman M;Audrey S

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通过一项提供更多同意机会的新政策的实施阶段,测试对不平等的影响和学校接受人乳头瘤病毒疫苗接种计划的情况。英格兰西南部的两个地方当局。年轻女性(n=7129)在干预期间(2017/2018至2018/2019计划年)常规符合12-13岁HPV疫苗接种条件。当地政策变化,包括提供同意的额外机会(父母口头同意和青少年自我同意)。对横断面干预数据进行了二次分析,以检查以下方面的接受情况:(1)收到父母书面同意书;(2)按实施阶段划分的未接种疫苗的年轻妇女的百分比。在干预期间,6341名(89.0%)符合条件的年轻女性开始了HPV疫苗接种系列。如果年轻女性就读于替代教育机构(p<0.001),属于非白人英国族裔群体(p <0.01)或更贫困的五分之一(p<0.001),则父母书面同意书不太可能被归还。父母口头同意和青少年自我同意的实施将未接种疫苗的年轻妇女的比例从21.3%降至16.5%(风险差异:4.8%)。与最贫困的五分之一相比,属于最贫困的年轻女性的影响更大(风险差异:7.4% vs 2.3%,p<0.001),与白色英国年轻女性相比,属于未知种族类别的年轻女性的影响更大(6.7% vs 4.2%,p<0.001)。非白人英国年轻女性(5.4%,p<0.21)没有发现差异。当地对同意程序的政策改变,允许父母口头同意和青少年自我同意,克服了家庭中年轻妇女接种疫苗的一些障碍,这些家庭不太可能对获得同意的纸质方法作出反应,患宫颈癌的风险更大。49086105.
To test the impact on inequalities and uptake of the schools-based human papillomavirus (HPV) vaccination programme by stage of implementation of a new policy providing additional opportunities to consent. Two local authorities in the south-west of England. Young women (n=7129) routinely eligible for HPV vaccination aged 12–13 years during the intervention period (2017/2018 to 2018/2019 programme years). Local policy change that included additional opportunities to provide consent (parental verbal consent and adolescent self-consent). Secondary analyses of cross-sectional intervention data were undertaken to examine uptake by: (1) receipt of parental written consent forms and; (2) percentage of unvaccinated young women by stage of implementation. During the intervention period, 6341 (89.0%) eligible young women initiated the HPV vaccination series. Parental written consent forms were less likely to be returned where young women attended alternative education provider settings (p<0.001), belonged to non-white British ethnic groups (p<0.01) or more deprived quintiles (p<0.001). Implementation of parental verbal consent and adolescent self-consent reduced the percentage of unvaccinated young women from 21.3% to 16.5% (risk difference: 4.8%). The effect was greater for young women belonging to the most deprived compared with the least deprived quintile (risk difference: 7.4% vs 2.3%, p<0.001), and for young women classified as Unknown ethnic category compared with white British young women (6.7% vs 4.2%, p<0.001). No difference was found for non-white British young women (5.4%, p<0.21). Local policy change to consent procedures that allowed parents to consent verbally and adolescents to self-consent overcame some of the barriers to vaccination of young women belonging to families less likely to respond to paper-based methods of gaining consent and at greater risk of developing cervical cancer. 49 086 105.
DOI: 10.1016/s2468-2667(17)30238-4
发表时间: 2018-01
期刊: The Lancet. Public health
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作者:
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期刊: Journal of public health (Oxford, England)
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作者:
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DOI: 10.1093/pubmed/fdv073
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期刊: Journal of public health (Oxford, England)
影响因子: --
作者:
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DOI: 10.1016/j.vaccine.2020.09.074
发表时间: 2020-11-03
期刊: Vaccine
影响因子: 5.5
作者:
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