Development and preliminary testing of the new five-level version of EQ-5D (EQ-5D-5L).

Development and preliminary testing of the new five-level version of EQ-5D (EQ-5D-5L).
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DOI:
10.1007/s11136-011-9903-x
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发表时间:
2011-12
影响因子:
3.5
通讯作者:
Badia, X.
Badia, X.
中科院分区:
医学2区
文献类型:
--
作者:
Herdman, M.;Gudex, C.;Lloyd, A.;Janssen, M. F.;Kind, P.;Parkin, D.;Bonsel, G.;Badia, X.

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本文介绍了新的5级EQ-5D(EQ-5D-5L)健康状况测量。EQ-5D目前在五个维度上使用三个严重程度来衡量健康。成立了一个EuroQol Group特别工作组,以寻找通过增加严重程度的数量来提高仪器的灵敏度和减少上限影响的方法。这项研究在英国和西班牙进行。使用响应量表确定每个维度中5个级别的严重性标签。焦点小组被用来调查新版本的表面和内容的有效性,包括那些版本产生的假设健康状态。选择大约第25、50和75个百分位数的标签会产生两个可选的5级版本。在EQ-5D的功能维度中,焦点小组的工作显示出轻微-中度-严重的问题,而“没有问题”和“无法做”这两个词是最重要的。在疼痛/不适和焦虑/抑郁维度上也使用了类似的措辞。虽然参与者强调健康状态的内部一致性的必要性,但人们很好地理解了假设的健康状态。EuroQol集团已经开发了EQ-5D的5级版本。还需要进一步的测试,以确定新版本是否提高了敏感度并减少了天花板效应。
This article introduces the new 5-level EQ-5D (EQ-5D-5L) health status measure. EQ-5D currently measures health using three levels of severity in five dimensions. A EuroQol Group task force was established to find ways of improving the instrument’s sensitivity and reducing ceiling effects by increasing the number of severity levels. The study was performed in the United Kingdom and Spain. Severity labels for 5 levels in each dimension were identified using response scaling. Focus groups were used to investigate the face and content validity of the new versions, including hypothetical health states generated from those versions. Selecting labels at approximately the 25th, 50th, and 75th centiles produced two alternative 5-level versions. Focus group work showed a slight preference for the wording ‘slight-moderate-severe’ problems, with anchors of ‘no problems’ and ‘unable to do’ in the EQ-5D functional dimensions. Similar wording was used in the Pain/Discomfort and Anxiety/Depression dimensions. Hypothetical health states were well understood though participants stressed the need for the internal coherence of health states. A 5-level version of the EQ-5D has been developed by the EuroQol Group. Further testing is required to determine whether the new version improves sensitivity and reduces ceiling effects.
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