The role of low cognitive effort and negative symptoms in neuropsychological impairment in schizophrenia.

The role of low cognitive effort and negative symptoms in neuropsychological impairment in schizophrenia.
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低认知努力和阴性症状在精神分裂症神经心理损伤中的作用。

DOI:
10.1037/neu0000113
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发表时间:
2015
期刊:
影响因子:
2.4
通讯作者:
Gold,JamesM
Gold,JamesM
中科院分区:
心理学3区
文献类型:
--
作者:
Strauss,GregoryP;Morra,LindsayF;Sullivan,SaraK;Gold,JamesM

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目的探讨努力不足、负性症状(如爱恋、快感缺乏)和心理变量(如快感缺乏、对低认知资源的感知)对精神分裂症(SZ)患者全身性神经认知功能损害的预测作用。方法在实验一中,97例SZ患者和63例健康对照(CN)完成维多利亚症状效度测验(VSVT)、Matrics共识认知成套测验(MCCB)和自填性快感缺乏问卷。在实验2中,46名SZ患者和33名CN患者完成了格林单词记忆测验(WMT)、MCCB量表以及快感缺失、失败主义绩效信念和消极期望评估的自我报告。结果表明,SZ患者的努力测试失败率较低(实验1为1.0%;实验2为15.2%);然而,低努力和阴性症状显著预测了整体神经认知障碍。结论低努力不影响大多数精神分裂症患者的神经心理测试结果的有效性;然而,努力测试对有严重阴性症状的SZ患者可能有用,他们可能更有可能因动机问题而付出不足的努力。尽管基本失败率相对较低,但在深圳筛选努力不足的人并将未通过努力测试的人排除在药物或认知补救试验之外可能是有益的。(心理信息数据库记录(C)2016 APA,保留所有权利)
ObjectiveTwo experiments were conducted to examine whether insufficient effort, negative symptoms (eg, avolition, anhedonia), and psychological variables (eg, anhedonia and perception of low cognitive resources) predict generalized neurocognitive impairment in individuals with schizophrenia (SZ).MethodIn Experiment 1, participants included 97 individuals with SZ and 63 healthy controls (CN) who completed the Victoria Symptom Validity Test (VSVT), the MATRICS Consensus Cognitive Battery (MCCB), and self-report anhedonia questionnaires. In Experiment 2, participants included 46 individuals with SZ and 33 CN who completed Green’s Word Memory Test (WMT), the MCCB, and self-reports of anhedonia, defeatist performance beliefs, and negative expectancy appraisals.ResultsResults indicated that a low proportion of individuals with SZ failed effort testing (1.0% Experiment 1; 15.2% Experiment 2); however, global neurocognitive impairment was significantly predicted by low effort and negative symptoms.ConclusionsFindings indicate that low effort does not threaten the validity of neuropsychological test results in the majority of individuals with schizophrenia; however, effort testing may be useful in SZ patients with severe negative symptoms who may be more likely to put forth insufficient effort due to motivational problems. Although the base rate of failure is relatively low, it may be beneficial to screen for insufficient effort in SZ and exclude individuals who fail effort testing from pharmacological or cognitive remediation trials.(PsycINFO Database Record (c) 2016 APA, all rights reserved)
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