Sexually transmitted infections and infectiousness beliefs among people living with HIV/AIDS: implications for HIV treatment as prevention.

Sexually transmitted infections and infectiousness beliefs among people living with HIV/AIDS: implications for HIV treatment as prevention.
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DOI:
10.1111/j.1468-1293.2009.00818.x
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发表时间:
2010-09
期刊:
影响因子:
3
通讯作者:
Cherry C
Cherry C
中科院分区:
医学4区
文献类型:
--
作者:
Kalichman SC;Eaton L;Cherry C

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性传播感染(STI)严重影响艾滋病毒/艾滋病患者的健康,增加了艾滋病毒的传染性,从而增加了传染性。目前的研究对490名艾滋病毒阳性男性和女性的社区样本进行了STI检查。机密的电脑访谈是在社区研究环境中收集的。在这项研究中,14%的艾滋病毒/艾滋病患者在六个月内被诊断出患有新的性传播感染。在这段时间内,患有新性传播感染的人有明显更多的性伴侣,包括非艾滋病毒阳性伴侣。与未感染STI的参与者相比,感染STI的参与者明显更有可能具有可检测到的病毒载量,而不太可能知道他们的病毒载量。多变量分析显示,认为无法检测到的病毒载量会导致传染性降低与感染新的性传播感染有关。那些认为拥有无法检测到的病毒载量降低艾滋病毒传播风险的人更有可能是传染性的,因为性传播感染合并感染。旨在利用艾滋病毒治疗预防艾滋病毒的方案必须解决传染性观念,并积极控制艾滋病毒/艾滋病患者的性传播感染。
Sexually transmitted infections (STI) significantly impact the health of people living with HIV/AIDS, increasing HIV infectiousness and therefore transmissibility. The current study examined STI in a community sample of 490 HIV positive men and women. Confidential computerized interviews were collected in a community research setting. 14% of the people living with HIV/AIDS in this study had been diagnosed with a new STI in a six month period. Individuals with a new STI had significantly more sex partners in that time period, including non-HIV positive partners. Participants who had contracted an STI were significantly more likely to have detectable viral loads and were less likely to know their viral load than participants who did not contract an STI. Multivariate analysis showed that believing an undetectable viral load leads to lower infectiousness was associated with contracting a new STI. Individuals who believe having an undetectable viral load reduces HIV transmission risks were more likely infectious because of STI co-infection. Programs that aim to use HIV treatment for HIV prevention must address infectiousness beliefs and aggressively control STI among people living with HIV/AIDS.
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