The ARTS web server for aligning RNA tertiary structures.
The ARTS web server for aligning RNA tertiary structures.
复制标题
用于对齐RNA三级结构的艺术Web服务器。
DOI:
10.1093/nar/gkl312
复制
发表时间:
2006-07-01
影响因子:
14.9
通讯作者:
Wolfson, Haim J.
中科院分区:
文献类型:
--
作者:
Dror, Oranit;Nussinov, Ruth;Wolfson, Haim J.
RNA molecules with common structural features may share similar functional properties. Structural comparison of RNAs and detection of common substructures is, thus, a highly important task. Nevertheless, the current available tools in the RNA community provide only a partial solution, since they either work at the 2D level or are suitable for detecting predefined or local contiguous tertiary motifs only. Here, we describe a web server built around ARTS, a method for aligning tertiary structures of nucleic acids (both RNA and DNA). ARTS receives a pair of 3D nucleic acid structures and searches for a priori unknown common substructures. The search is truly 3D and irrespective of the order of the nucleotides on the chain. The identified common substructures can be large global folds with hundreds and even thousands of nucleotides as well as small local motifs with at least two successive base pairs. The method is highly efficient and has been used to conduct an all-against-all comparison of all the RNA structures in the Protein Data Bank. The web server together with a software package for download are freely accessible at .
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影响因子:
5.8
作者:
Dror, O;Nussinov, R;Wolfson, H
通讯作者:
Wolfson, H
影响因子:
14.9
作者:
Yang, HW;Jossinet, F;Westhof, E
通讯作者:
Westhof, E
影响因子:
16.8
作者:
Golden, BL;Kim, H;Chase, E
通讯作者:
Chase, E
DOI:
10.1021/ci0103626
发表时间:
2001-09-01
期刊:
JOURNAL OF CHEMICAL INFORMATION AND COMPUTER SCIENCES
影响因子:
--
作者:
Reijmers, TH;Wehrens, R;Buydens, LMC
通讯作者:
Buydens, LMC
影响因子:
5.6
作者:
Gendron, P;Lemieux, S;Major, F
通讯作者:
Major, F