Hypoxia, stem cells and bone tumor.

Hypoxia, stem cells and bone tumor.
复制标题

DOI:
10.1016/j.canlet.2011.09.023
复制
发表时间:
2011-12-27
期刊:
影响因子:
9.7
通讯作者:
Wei, Yiyong
Wei, Yiyong
中科院分区:
医学1区
文献类型:
--
作者:
Zeng, Wen;Wan, Rong;Zheng, Yuehuan;Singh, Shree Ram;Wei, Yiyong

文献摘要

参考文献

被引文献

相似文献

正常的氧水平对生态位至关重要,它与生态位的其他组成部分一起在调节干细胞或肿瘤细胞的行为中起着至关重要的作用。缺氧在包括实体瘤生长在内的正常发育和疾病进展中起着重要作用。缺氧诱导因子(hif)是细胞对缺氧反应的关键介质。本文就hif在骨肿瘤形成中的作用作一综述。此外,我们还强调了缺氧、干细胞及其生态位如何调节骨肿瘤的发生。
Normal oxygen level is critical for niches that together with other components of the niche play vital role in regulating stem or tumor cells behavior. Hypoxia plays an important role in normal development and disease progression, including the growth of solid tumors. The hypoxia inducible factors (HIFs) are the key mediators of the cellular response to hypoxia. In this review, we focused on the role of HIFs on bone tumor formation. Further, we also emphasized how hypoxia, stem cells, and its niches regulate the bone tumorigenesis.
DOI: 10.4161/cc.8.20.9701
发表时间: 2009-10-15
期刊: Cell cycle (Georgetown, Tex.)
影响因子: --
作者:
Heddleston JM;Li Z;McLendon RE;Hjelmeland AB;Rich JN
通讯作者: Rich JN
DOI: 10.1016/s0022-5347(01)65919-6
发表时间: 1996-08-01
期刊: JOURNAL OF UROLOGY
影响因子: 6.6
作者:
Cramer, SD;Chen, ZX;Peehl, DM
通讯作者: Peehl, DM
DOI: 10.1096/fj.08-102590
发表时间: 2008-10-01
期刊: FASEB JOURNAL
影响因子: 4.8
作者:
Bussolati, Benedetta;Bruno, Stefania;Camussi, Giovanni
通讯作者: Camussi, Giovanni
DOI: 10.1016/j.juro.2009.12.092
发表时间: 2010-05
期刊: The Journal of urology
影响因子: --
作者:
Bae KM;Su Z;Frye C;McClellan S;Allan RW;Andrejewski JT;Kelley V;Jorgensen M;Steindler DA;Vieweg J;Siemann DW
通讯作者: Siemann DW
DOI: 10.1158/1078-0432.ccr-06-1007
发表时间: 2006-10-15
影响因子: 11.5
作者:
Guise, Theresa A.;Mohammad, Khalid S.;Chirgwin, John M.
通讯作者: Chirgwin, John M.