The Primary Structure of the Inhibitor of Tissue Plasminogen Activator Found in the Seeds of Erythrina caffra
The Primary Structure of the Inhibitor of Tissue Plasminogen Activator Found in the Seeds of Erythrina caffra
复制标题
刺桐种子中组织纤溶酶原激活剂抑制剂的一级结构
DOI：
10.1055/s-0038-1651133
复制
发表时间：
1987
影响因子：
6.7
通讯作者：
E. Dowdle
中科院分区：
文献类型：
--
作者：
F. Joubert;E. Dowdle
Summary Trypsin and tissue plasminogen activator inhibitor DE-3 from Erythrina caffra contains 172 amino acids, including 4 half-cystine residues, and resembles the Kunitz-type inhibitors. Limited hydrolysis of DE-3 with trypsin at pH 3.2 produced two fragments, FI and F2, containing 63 and 109 amino acids, respectively. Amino-terminal sequence studies showed that FI was the N-terminal and that F2 was the C-terminal fragment. The complete amino acid sequence of the fragments were then determined on peptides produced by enzymatic digestion with trypsin. The sequence of trypsin and tissue plasminogen activator inhibitor DE-3 from E. caffra seeds shows a high degree of homology to that of trypsin and tissue plasminogen activator inhibitor DE-3 from E. latissima seeds and revealed only four amino acids which were replaced.
影响因子：
2.9
作者：
WOLFENDEN, R;ANDERSSON, L;SOUTHGATE, CCB
通讯作者：
SOUTHGATE, CCB
影响因子：
56.9
作者：
Bergmann;K. Fox;M. Ter-pogossian;B. Sobel;D. Collen
通讯作者：
Bergmann;K. Fox;M. Ter-pogossian;B. Sobel;D. Collen