Evaluation of routinely collected records for dementia outcomes in UK: a prospective cohort study.
Evaluation of routinely collected records for dementia outcomes in UK: a prospective cohort study.
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DOI：
10.1136/bmjopen-2022-060931
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发表时间：
2022-06-15
期刊：
影响因子：
2.9
通讯作者：
Brayne, Carol
中科院分区：
文献类型：
--
作者：
Hayat, Shabina;Luben, Robert;Khaw, Kay-Tee;Wareham, Nicholas;Brayne, Carol
评估在不同常规收集的记录中记录为痴呆症诊断的个体的特征，并检查数据源中痴呆症编码的重叠程度。此外，目前的二级和初级保健记录的比较提供价值的研究人员使用常规收集的记录痴呆症的结果捕获。前瞻性队列研究。一个由诺福克的25639名男性和女性组成的队列，招募时年龄为40-79岁（1993-1997年），随访至2018年，与常规收集的痴呆症病例相关。数据来源包括死亡证明和国家卫生服务（NHS）医院或二级保健记录的死亡率。还审查了队列中一个子集的初级保健记录。痴呆症的诊断（任何原因）。超过2000名参与者（n=2635人）被发现在一个或多个检查的数据源中记录了痴呆症诊断。在二级护理数据来源中观察到有限的一致性。我们还观察到该亚组与初级保健记录的差异，并报告了潜在的联系相关的选择偏倚。使用不同类型的记录链接从英国的卫生系统的不同部分揭示了记录的痴呆症诊断的差异，表明痴呆症可以在不同程度上确定在不同的NHS系统的不同部分。然而，在所确定的领域中存在着相当大的差异和有限的重叠。我们提出了潜在的选择偏差，可能会发生取决于死亡原因，或初级和二级保健数据源。随着常规收集的健康数据的使用范围的扩大，研究人员必须意识到这些潜在的偏见和不准确性，仔细报告他们使用的数据源的局限性和挑战的可能程度。
To evaluate the characteristics of individuals recorded as having a dementia diagnosis in different routinely collected records and to examine the extent of overlap of dementia coding across data sources. Also, to present comparisons of secondary and primary care records providing value for researchers using routinely collected records for dementia outcome capture. A prospective cohort study. A cohort of 25 639 men and women in Norfolk, aged 40–79 years at recruitment (1993–1997) followed until 2018 linked to routinely collected to identify dementia cases. Data sources include mortality from death certification and National Health Service (NHS) hospital or secondary care records. Primary care records for a subset of the cohort were also reviewed. Diagnosis of dementia (any-cause). Over 2000 participants (n=2635 individuals) were found to have a dementia diagnosis recorded in one or more of the data sources examined. Limited concordance was observed across the secondary care data sources. We also observed discrepancies with primary care records for the subset and report on potential linkage-related selection bias. Use of different types of record linkage from varying parts of the UK’s health system reveals differences in recorded dementia diagnosis, indicating that dementia can be identified to varying extents in different parts of the NHS system. However, there is considerable variation, and limited overlap in those identified. We present potential selection biases that might occur depending on whether cause of death, or primary and secondary care data sources are used. With the expansion of using routinely collected health data, researchers must be aware of these potential biases and inaccuracies, reporting carefully on the likely extent of limitations and challenges of the data sources they use.
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影响因子：
3.1
作者：
Ford, Elizabeth;Boyd, Andy;Sperrin, Matthew
通讯作者：
Sperrin, Matthew
影响因子：
6.7
作者：
Davis KAS;Mueller C;Ashworth M;Broadbent M;Jewel A;Molokhia M;Perera G;Stewart RJ
通讯作者：
Stewart RJ
痴呆症的流行病学病理：医学研究委员会认知功能和衰老研究中死亡的可归因风险。
影响因子：
15.8
作者：
Matthews FE;Brayne C;Lowe J;McKeith I;Wharton SB;Ince P
通讯作者：
Ince P
影响因子：
2.9
作者：
Russell, Paul;Banerjee, Sube;Flaherty, Breda
通讯作者：
Flaherty, Breda
影响因子：
15.8
作者：
Brayne, Carol;Gao, Lu;Matthews, Fiona E.
通讯作者：
Matthews, Fiona E.