Development and validation of the Penn Arthralgia Aging Scale among breast cancer survivors.
Development and validation of the Penn Arthralgia Aging Scale among breast cancer survivors.
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作者：
Brier MJ;Chambless DL;Lee L;Mao JJ
芳香化酶抑制剂治疗的乳腺癌幸存者经常经历关节疼痛作为其治疗的副作用；定性调查表明，这种关节痛可能会导致女性觉得自己比正常年龄衰老得更快。为了进一步研究这一经验，我们开发了Penn关节痛老化量表（PAAS）。本报告描述了PAAS在不同种族的患有关节疼痛的乳腺癌幸存者样本中的发展和验证。量表的项目是从对患者访谈的内容分析中开发出来的。该量表进行了试点测试，并根据患者反馈进行了修改。随后，556名认可关节疼痛的乳腺癌幸存者完成了8项PAAS。因子结构（采用探索性因子分析）、内部一致性、收敛效度、发散效度和增量效度进行检验。所得量表具有单因素结构，具有较强的内部一致性（Cronbach 's alpha=0.94），具有收敛效度和发散效度：PAAS与关节疼痛严重程度显著相关（r = 0.55, p < 0.01），与实际年龄相关性较小且不显著（r = - 0.07, p = 0.10）。PAAS也被发现可以预测焦虑、抑郁和疼痛干扰结果的增量方差。这些发现表明，PAAS产生了可靠和有效的评分，可以捕捉到乳腺癌幸存者对关节痛引起的衰老的看法。随着进一步的研究，PAAS可能会促进我们对衰老的认知如何影响乳腺癌幸存者的情感、行为和临床结果的理解。
Breast cancer survivors on aromatase inhibitors often experience joint pain as a side effect of their treatment; qualitative investigations suggest that this arthralgia may cause women to feel they are aging faster than they should be. To facilitate further study of this experience, the Penn Arthralgia Aging Scale (PAAS) was developed. This report describes the development and validation of the PAAS in a racially diverse sample of breast cancer survivors suffering from joint pain. Items of the scale were developed from a content analysis of interviews with patients. The scale was pilot-tested and modifications were made based on patient feedback. Subsequently, 556 breast cancer survivors who endorsed joint pain completed the eight-item PAAS. Factor structure (using exploratory factor analysis), internal consistency, and convergent, divergent, and incremental validity were examined. The resulting scale had a one-factor structure with strong internal consistency (Cronbach’s alpha=0.94), and demonstrated both convergent and divergent validity: The PAAS was significantly correlated with joint pain severity (r = .55, p < 0.01) and had a small and non-significant correlation with actual age (r = −0.07, p = 0.10). The PAAS was also found to predict incremental variance in anxiety, depression, and pain interference outcomes. These findings suggest that the PAAS produced reliable and valid scores that capture perceptions of aging due to arthralgia among breast cancer survivors. With further research, the PAAS may advance our understanding of how perceptions of aging may affect breast cancer survivors’ emotional, behavioral and clinical outcomes.
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影响因子：
45.3
作者：
CLARK, GM;OSBORNE, CK;MCGUIRE, WL
通讯作者：
MCGUIRE, WL
影响因子：
45.3
作者：
Henry, N. Lynn;Azzouz, Faouzi;Storniolo, Anna Maria
通讯作者：
Storniolo, Anna Maria
影响因子：
2.9
作者：
Holzberg, AD;Robinson, ME;Gremillion, HA
通讯作者：
Gremillion, HA
影响因子：
3.6
作者：
Clark, LA;Watson, D
通讯作者：
Watson, D
影响因子：
45.3
作者：
Partridge, Ann H.;LaFountain, Andrea;Asnis-Alibozek, Aviva
通讯作者：
Asnis-Alibozek, Aviva