Clinical recommendations for cardiovascular magnetic resonance mapping of T1, T2, T2* and extracellular volume: A consensus statement by the Society for Cardiovascular Magnetic Resonance (SCMR) endorsed by the European Association for Cardiovascular Imaging (EACVI).
Clinical recommendations for cardiovascular magnetic resonance mapping of T1, T2, T2* and extracellular volume: A consensus statement by the Society for Cardiovascular Magnetic Resonance (SCMR) endorsed by the European Association for Cardiovascular Imaging (EACVI).
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DOI：
10.1186/s12968-017-0389-8
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发表时间：
2017-10-09
期刊：
影响因子：
--
通讯作者：
Friedrich MG
中科院分区：
文献类型：
--
作者：
Messroghli DR;Moon JC;Ferreira VM;Grosse-Wortmann L;He T;Kellman P;Mascherbauer J;Nezafat R;Salerno M;Schelbert EB;Taylor AJ;Thompson R;Ugander M;van Heeswijk RB;Friedrich MG
参数标测技术提供了一种非侵入性工具，用于量化符合心血管磁共振（CMR）条件的心肌疾病中的组织改变。CMR的参数标测现在允许基于T1、T2和T2*（星星）弛豫时间和细胞外容积（ECV）的变化对心肌组成的变化进行常规空间可视化和定量。这些变化包括主要与心肌细胞的细胞内紊乱相关的特定疾病途径（例如，铁超负荷或Anderson-Fabry病中的鞘糖脂积累）;心肌线粒体中的细胞外紊乱（例如，心肌纤维化或分别由胶原或淀粉样蛋白积累引起的心脏淀粉样变性）;或两者（心肌水肿伴细胞内和/或细胞外水增加）。参数映射通过定量诊断、患者间和患者内可比性的进步以及治疗的相关改进来改善患者护理。有许多技术方法和潜在的应用。本文件总结了截至2017年年中心脏参数标测临床价值的现有证据，并为科学家、临床医生和CMR制造商在不同临床场景中的实际使用提供了建议。
Parametric mapping techniques provide a non-invasive tool for quantifying tissue alterations in myocardial disease in those eligible for cardiovascular magnetic resonance (CMR). Parametric mapping with CMR now permits the routine spatial visualization and quantification of changes in myocardial composition based on changes in T1, T2, and T2*(star) relaxation times and extracellular volume (ECV). These changes include specific disease pathways related to mainly intracellular disturbances of the cardiomyocyte (e.g., iron overload, or glycosphingolipid accumulation in Anderson-Fabry disease); extracellular disturbances in the myocardial interstitium (e.g., myocardial fibrosis or cardiac amyloidosis from accumulation of collagen or amyloid proteins, respectively); or both (myocardial edema with increased intracellular and/or extracellular water). Parametric mapping promises improvements in patient care through advances in quantitative diagnostics, inter- and intra-patient comparability, and relatedly improvements in treatment. There is a multitude of technical approaches and potential applications. This document provides a summary of the existing evidence for the clinical value of parametric mapping in the heart as of mid 2017, and gives recommendations for practical use in different clinical scenarios for scientists, clinicians, and CMR manufacturers.
DOI：
10.1186/s12968-017-0389-8
发表时间：
2017-10-09
期刊：
Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance
影响因子：
--
作者：
Messroghli DR;Moon JC;Ferreira VM;Grosse-Wortmann L;He T;Kellman P;Mascherbauer J;Nezafat R;Salerno M;Schelbert EB;Taylor AJ;Thompson R;Ugander M;van Heeswijk RB;Friedrich MG
通讯作者：
Friedrich MG
影响因子：
2.1
作者：
Reiter U;Reiter G;Asslaber M;Dacar D;Maderthaner R;Binder J;Greiser A;Beer M;Fuchsjäger M
通讯作者：
Fuchsjäger M