Age-dependent Electroencephalogram Characteristics During Different Levels of Anesthetic Depth.
Age-dependent Electroencephalogram Characteristics During Different Levels of Anesthetic Depth.
复制标题
不同麻醉深度水平下年龄相关的脑电图特征。
DOI：
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发表时间：
2022
影响因子：
2
通讯作者：
Yonghao Yu
中科院分区：
文献类型：
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作者：
Feixiang Li;Yaoyao Dang;Xuan Zhang;Huiming Chen;Yuechun Lu;Yonghao Yu
目的：目前基于脑电图推导的麻醉深度监测方法尚不适应年龄的变化。本文分析了年龄因素对脑电图特征的影响。方法对80例正常成人进行常规麻醉时的额面脑电图记录。观察四种麻醉方式下脑电图随年龄和麻醉方式的变化特点。结果慢波功率、δ功率、脑电双频指数（BIS）和近似熵能区分不同麻醉状态（P < 0.05）。在深麻醉和极深麻醉状态下，δ功率随年龄增长而下降（P < 0.0001）。在极深麻醉状态下，θ功率随年龄增长而降低（P < 0.05）。在深度和极深度麻醉状态下，α功率随年龄增长而下降（P = 0.0002）。在浅麻醉和深麻醉状态下，β功率随年龄增长而下降（P = 0.003）。在深度麻醉状态下，γ功率随年龄增长而降低（P = 0.002）。在极深麻醉状态下，排列熵随年龄的增长而显著增加（P = 0.0001）。在极深麻醉状态下，BIS值随年龄增长而增加（P = 0.006）。慢波功率、近似熵和样品熵没有表现出年龄依赖性的变化。结论采用BIS和δ功率监测麻醉深度时应考虑年龄的影响，而采用慢波功率和近似熵监测麻醉深度时不应考虑年龄的影响。
Objective The monitoring of anesthetic depth based on electroencephalogram derivation is not currently adjusted for age. Here we analyze the influence of age factors on electroencephalogram characteristics. Methods Frontal electroencephalogram recordings were obtained from 80 adults during routine clinical anesthesia. The characteristics of electroencephalogram with age and anesthesia were observed during four kinds of anesthesia. Results The slow wave power, δ power, Bispectral Index (BIS) and approximate entropy can be used to distinguish different states of anesthesia (P < 0.05). In the deep and very deep anesthesia states, δ power decreased with age (P < 0.0001). In the very deep anesthesia state, θ power decreased with age (P < 0.05). In the deep and very deep anesthesia states, α power decreased with age (P = 0.0002). In the light and deep anesthesia states, β power decreased with age (P = 0.003). In the deep anesthesia state, γ power decreased with age (P = 0.002). In the very deep anesthesia state, permutation entropy increased significantly with age (P = 0.0001). In the very deep anesthesia state, BIS value increased with age (P = 0.006). The slow wave power, approximate entropy, and sample entropy did not show age-dependent changes. Conclusions The influence of age should be considered when using BIS and δ power to monitor the depth of anesthesia, while the influence of age should not be considered when using slow wave power and approximate entropy to monitor the depth of anesthesia.
影响因子：
3.7
作者：
Fjell, Anders M.;Westlye, Lars T.;Walhovd, Kristine B.
通讯作者：
Walhovd, Kristine B.
影响因子：
3.7
作者：
Fjell, Anders M.;Westlye, Lars T.;Walhovd, Kristine B.
通讯作者：
Walhovd, Kristine B.
影响因子：
3.7
作者：
Raz, N;Lindenberger, U;Acker, JD
通讯作者：
Acker, JD