Meniscal T1rho and T2 measured with 3.0T MRI increases directly after running a marathon.
Meniscal T1rho and T2 measured with 3.0T MRI increases directly after running a marathon.
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DOI：
10.1007/s00256-010-1058-2
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发表时间：
2011-06
影响因子：
2.1
通讯作者：
Link, Thomas M.
中科院分区：
文献类型：
--
作者：
Stehling, Christoph;Luke, Anthony;Stahl, Robert;Baum, Thomas;Joseph, Gabby;Pan, Judong;Link, Thomas M.
应用3.0 T MRI前瞻性评价马拉松运动员无症状膝关节半月板T1rho和T2松弛时间的变化，并与年龄匹配的健康受试者进行比较。13名马拉松运动员在比赛前、比赛后48-72小时和比赛后3个月分别接受了3.0 T MRI检查，包括T1rho和T2图谱。10名对照者在基线和3个月后接受检查。所有图像由两名肌肉骨骼放射科医生进行分析，对软骨、半月板、韧带进行识别和分级。以及其他膝关节异常的WORMS评分。半月板分割生成6个区室的T1rho和T2图谱。马拉松前后膝关节形态异常无明显差异。然而，所有马拉松运动员在比赛后所有半月板间室的T1rho和T2值均显著增加（p < 0.0001），这可能表明半月板组织的生化组成发生了变化。虽然T2值在3个月后下降，但T1rho值仍保持在较高水平，表明马拉松后半月板基质成分持续变化。半月板的T2值有可能被用作识别可逆性半月板基质变化的生物标志物，表明潜在的组织损伤。T1rho值需要进一步研究，但可能是诊断半月板运动后早期退行性改变的有价值的标志。
To prospectively evaluate changes in T1rho and T2 relaxation time in the meniscus using 3.0 T MRI in asymptomatic knees of marathon runners and to compare these findings with those of age-matched healthy subjects. Thirteen marathon runners underwent 3.0 T MRI including T1rho and T2 mapping sequences before, 48–72 h after, and 3 months after competition. Ten controls were examined at baseline and after 3 months. All images were analyzed by two musculoskeletal radiologists identifying and grading cartilage, meniscal, ligamentous. and other knee abnormalities with WORMS scores. Meniscal segmentation was performed to generate T1rho and T2 maps in six compartments. No differences in morphological knee abnormalities were found before and after the marathon. However, all marathon runners showed a significant increase in T1rho and T2 values after competition in all meniscus compartments (p < 0.0001), which may indicate changes in the biochemical composition of meniscal tissue. While T2 values decreased after 3 months T1rho values remained at a high level, indicating persisting changes in the meniscal matrix composition after a marathon. T2 values in menisci have the potential to be used as biomarkers for identifying reversible meniscus matrix changes indicating potential tissue damage. T1rho values need further study, but may be a valuable marker for diagnosing early, degenerative changes in the menisci following exercise.
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