Impairment by damage of the pterygopalatine ganglion of nitroxidergic vasodilator nerve function in canine cerebral and retinal arteries.
Impairment by damage of the pterygopalatine ganglion of nitroxidergic vasodilator nerve function in canine cerebral and retinal arteries.
复制标题
犬脑动脉和视网膜动脉中硝基氧能血管舒张神经功能的翼腭神经节损伤导致的损伤。
DOI：
10.1161/01.res.72.1.206
复制
发表时间：
1993
影响因子：
20.1
通讯作者：
T. Okamura
中科院分区：
文献类型：
--
作者：
Noboru Toda;K. Ayajiki;Kazuhide Yoshida;Hiroshi Kimura;T. Okamura
Histochemical study revealed that transcutaneous injection of ethanol into the vicinity of the pterygopalatine ganglion greatly decreased the positive staining for NADPH diaphorase activity after 1 week in the ipsilateral ganglion of a dog and abolished the staining of perivascular nerves in the middle and posterior cerebral arteries. Transmural electrical stimulation or nicotine produced a relaxation in middle and posterior cerebral arteries isolated from the side with the nontreated ganglion (control side), whereas the relaxation was abolished or reversed to a contraction in the arteries from the side with the ethanol-treated ganglion. Nitric oxide-induced relaxations did not differ in the arteries from both sides. The response to nerve stimulation of the control arteries was suppressed by treatment with NG-nitro-L-arginine (L-NA), an inhibitor of nitric oxide synthase, and the inhibition was reversed by L-arginine. Nicotine produced a contraction followed by a relaxation in central retinal arterial strips obtained from the control side; the relaxation was abolished and the contraction was potentiated in the arteries from the treated side. The nicotine-induced relaxation was abolished by L-NA, and the contraction was suppressed by phentolamine. On the other hand, the nicotine-induced relaxation in superficial temporal arteries, susceptible to L-NA, was not attenuated by treatment with ethanol. The findings obtained so far support our hypothesis that nitric oxide released from the vasodilator nerve acts as a transmitter to produce arterial smooth muscle relaxation and suggest that the nerve fibers to the cerebral and retinal arteries arise from the pterygopalatine ganglion.
DOI：
--
发表时间：
1985-03
期刊：
The Journal of pharmacology and experimental therapeutics
影响因子：
--
作者：
W. Martin;G. Villani;D. Jothianandan;R. Furchgott
通讯作者：
W. Martin;G. Villani;D. Jothianandan;R. Furchgott
血管平滑肌源性松弛因子（MDRF）及其与一氧化氮的密切相似性。
DOI：
10.1016/0006-291x(90)91243-l
发表时间：
1990
影响因子：
3.1
作者：
Wood,KS;Buga,GM;Byrns,RE;Ignarro,LJ
通讯作者：
Ignarro,LJ
供应大鼠眼睛的自主神经元和血管活性肠多肽（VIP）样免疫反应性的眼眶内分布。
影响因子：
3.4
作者：
Kuwayama,Y;Grimes,PA;Ponte,B;Stone,RA
通讯作者：
Stone,RA