The toxins of group A streptococcus, the flesh eating bacteria.

The toxins of group A streptococcus, the flesh eating bacteria.
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A 族链球菌(食肉细菌)的毒素。

DOI:
10.3109/08820139709048921
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发表时间:
1997
影响因子:
2.8
通讯作者:
D. Stevens
D. Stevens
中科院分区:
医学4区
文献类型:
--
作者:
D. Stevens

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化脓性链球菌在世界上大多数国家的所有年龄段的个体中引起各种各样的感染。由于这些感染发生的频率,医生非常熟悉与A组链球菌相关的临床表现的多样性。然而,在20世纪80年代后期,出现了一种严重的链球菌感染形式,即链球菌中毒性休克综合征,并持续了过去10年。这种综合征与侵袭性软组织感染、休克和器官衰竭的早期发作有关。本文简要介绍链球菌中毒性休克综合征的流行病学和临床特点,强调链球菌产生的毒素在其中的作用。化脓性肉芽肿在该病的发病机制中起作用。
Streptococcus pyogenes causes a wide variety of infections in individuals of all ages in most countries of the world. Because of the frequency with which these infections occur, physicians are quite familiar with the diversity of clinical presentations associated with the Group A streptococcus. Yet in the late 1980's, a severe form of streptococcal infection, the Streptococcal Toxic Shock Syndrome, emerged and has persisted for the last 10 years. This syndrome is associated with invasive soft tissue infections and the early onset of shock and organ failure. The purpose of this paper is to briefly describe the epidemiologic and clinical features of the Streptococcal Toxic Shock Syndromes and to emphasize the role that toxins produced by S. pyogenes play in the pathogenesis of this disease.
DOI: 10.1073/pnas.90.16.7676
发表时间: 1993-08-15
影响因子: 11.1
作者:
KAPUR, V;MAJESKY, MW;MUSSER, JM
通讯作者: MUSSER, JM
DOI: 10.1056/nejm198707163170305
发表时间: 1987-07-16
影响因子: 158.5
作者:
CONE, LA;WOODARD, DR;TOMORY, GS
通讯作者: TOMORY, GS
人类淋巴细胞对链球菌 M 蛋白结构确定的多肽片段的成细胞反应。
DOI: --
发表时间: 1981
期刊: Journal of immunology (Baltimore, Md. : 1950)
影响因子: --
作者:
Dale,JB;Simpson,WA;Ofek,I;Beachey,EH
通讯作者: Beachey,EH