Subacute Pain Trajectories following major musculoskeletal surgery in adolescents: A Pilot Study.

Subacute Pain Trajectories following major musculoskeletal surgery in adolescents: A Pilot Study.
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DOI:
10.1080/24740527.2020.1765692
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发表时间:
2020
期刊:
Canadian journal of pain = Revue canadienne de la douleur
影响因子:
--
通讯作者:
Zhou C
Zhou C
中科院分区:
其他
文献类型:
--
作者:
Rabbitts JA;Groenewald CB;Zhou C

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背景:接受大手术的青少年有很高的致残性急性和慢性术后疼痛(CPSP)发生率。然而,很少有人知道亚急性期时,急性到慢性疼痛的过渡发生。目的:本研究的目的是检查在大手术后的前30天内,在家中对青少年的疼痛和阿片类药物使用进行电子每日监测的可行性,并确定4个月时与CPSP相关的亚急性疼痛曲线的目标特征。研究方法:25名接受大型肌肉骨骼手术的青少年(10-18岁)在出院后30天每天晚上在简明疼痛量表上报告每日疼痛严重程度、干扰和阿片类药物使用情况,以形成短时间序列轨迹。在4个月时,年轻人报告了疼痛强度和健康相关的生活质量。根据4个月CPSP状态比较亚急性疼痛严重程度和干扰曲线的特征。结果:在4个月时,20.8%的青年符合CPSP标准。在30天的监测期间,继续发展CPSP的青年在45.9%的日子里报告了高疼痛严重程度,而恢复的青年为2.9%(P = 0.005),49.4%的日子里报告了高疼痛干扰,而恢复的青年为9.7%(P = 0.01)。在我们的试点样本中,疼痛变异性和变化率与CPSP无显著相关性。结论:我们发现在大手术后在家恢复的年轻人中收集日常疼痛数据是可行的。初步研究结果表明,日常电子监测可以发现术后早期恢复问题。需要更大规模的研究来验证亚急性疼痛轨迹特征,以确定CPSP的风险。
Background: Adolescents who undergo major surgery experience high rates of disabling acute and chronic postsurgical pain (CPSP). However, little is known about the subacute period when acute to chronic pain transition occurs. Aims: The aims of this study were to examine feasibility of electronic daily monitoring of pain and opioid use in adolescents during the first 30 days at home following major surgery and identify target features of subacute pain curves associated with CPSP at 4 months. Methods: Twenty-five youth (10–18 years) undergoing major musculoskeletal surgery reported daily pain severity, interference, and opioid use on the Brief Pain Inventory each evening for 30 days after hospital discharge to form short time series trajectories. At 4 months, youth reported on pain intensity and health-related quality of life. Characteristics of subacute pain severity and interference curves were compared by 4-month CPSP status. Results: At 4 months, 20.8% of youth met criteria for CPSP. During the 30-day monitoring period, youth who went on to develop CPSP reported high pain severity on 45.9% of days compared to 2.9% of days in youth who recovered (P = 0.005) and high pain interference on 49.4% of days vs. 9.7% in youth who recovered (P = 0.01). Pain variability and rate of change were not significantly associated with CPSP in our pilot sample. Conclusions: We found it feasible to collect daily pain data in youth recovering at home after major surgery. Pilot findings suggest that daily electronic monitoring may identify early recovery problems at home after surgery. Larger studies are needed to validate subacute pain trajectory features to identify risk for CPSP.
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期刊: MEDICAL CARE
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