Biodegradable Polymers in Drug Delivery Systems

Biodegradable Polymers in Drug Delivery Systems
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药物输送系统中的可生物降解聚合物

DOI:
10.1007/978-1-4614-0881-9_5
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发表时间:
2012
期刊:
Sensors (Basel, Switzerland)
影响因子:
--
通讯作者:
D. Burgess
D. Burgess
中科院分区:
--
文献类型:
--
作者:
J. Tsung;D. Burgess

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本章重点介绍生物可降解聚合物在长效注射给药系统中的应用,重点介绍已上市产品。概述了这些聚合物的化学结构和物理性质如何影响药物输送系统的功能,以及如何有策略地选择不同应用的聚合物。详细的例子,生物可降解的药物输送系统,讨论了有关的给药途径和疾病状态。读者将获得不同应用的聚合物选择信息,以及如何整合材料科学知识和配方,以战略性地设计不同病理状态的药物输送系统。
This chapter is focused on the use of biodegradable polymers in long acting injectable drug delivery systems with an emphasis on marketed products. An overview is provided of how the chemical structures and physical properties of these polymers impact functionality of drug delivery systems and how to strategically select polymers for different applications. Detailed examples of biodegradable drug delivery systems are discussed with respect to routes of administration and disease states. The reader will gain information on polymer selection for different applications and on how to integrate knowledge of materials science and formulations to strategically design drug delivery systems for different pathological states.
DOI: 10.1126/science.2218494
发表时间: 1990-09-28
期刊: SCIENCE
影响因子: 56.9
作者:
LANGER, R
通讯作者: LANGER, R