Cytology versus calcitonin assay in fine-needle aspiration biopsy wash-out fluid (FNAB-CT) in diagnosis of medullary thyroid microcarcinoma
Cytology versus calcitonin assay in fine-needle aspiration biopsy wash-out fluid (FNAB-CT) in diagnosis of medullary thyroid microcarcinoma
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细胞学与降钙素测定在细针抽吸活检冲洗液（FNAB-CT）中诊断甲状腺微小癌的效果
DOI：
10.1007/s12020-021-02759-1
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发表时间：
2021-03
期刊：
影响因子：
3.7
通讯作者：
Ye Lei
中科院分区：
文献类型：
--
作者：
Liu Ziyuan;Zhou Wenzhong;Han Rulai;Zhou Wei;Zhang Jie;Li Haorong;Wan Zhihan;Jin Yan;Shen Liyun;Zhou Yulin;Wang Shu;Chen Xi;Ye Lei
敏感超声检查的广泛使用导致甲状腺微核瘤（微MTC）的检测增加。这项前瞻性研究评估了细针运动活检细胞学（FNAB-C）和降钙素A的诊断精度
PurposeWidespread use of sensitive ultrasound examination led to an increasing detection of medullary thyroid microcarcinoma (micro-MTC). This prospective study evaluated the diagnostic accuracy of Fine-needle Aspiration Biopsy Cytology (FNAB-C) and calcitonin assay in Fine-needle Aspiration Biopsy wash-out fluid (FNAB-CT) in thyroid nodules less than 1 cm with elevated serum calcitonin(sCT).Methods87 thyroid nodules from 60 patients with elevated sCT (>10 pg/ml) were included and 51 were thyroid nodules less than 1cm. FNAB-CT and FNAB-C were performed to distinguish medullary thyroid carcinoma (MTC) lesions before surgery, histopathologic diagnoses served as main reference standards.ResultsFNAB-CT had a greater performance over FNAB-C for preoperative diagnosis of MTC (diagnostic accuracy: 98.85 vs 61.90%, sensitivity: 98.55 vs 55.07%, specificity: 100 vs 97.44%), especially for micro-MTC: FNAB-C established a sensitivity and diagnostic accuracy of 48.78 and 58% respectively, while FNAB-CT reached 97.56% sensitivity and 98.04% diagnostic accuracy.ConclusionsFNAB-CT demonstrated high diagnostic accuracy in diagnosing micro-MTC. Patients with microscopic thyroid nodules and elevated sCT level should perform FNAB-CT to exclude the diagnosis of MTC lesions.
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影响因子：
3.7
作者：
Moon, Hee Jung;Son, Eunju;Kwak, Jin Young
通讯作者：
Kwak, Jin Young
影响因子：
5.8
作者：
C. Nozières;L. Chardon;B. Goichot;F. Borson‐Chazot;V. Hervieu;K. Chikh;C. Lombard-Bohas;T. Walter
通讯作者：
C. Nozières;L. Chardon;B. Goichot;F. Borson‐Chazot;V. Hervieu;K. Chikh;C. Lombard-Bohas;T. Walter
DOI：
--
发表时间：
2017
期刊：
--
影响因子：
--
作者：
Kaliszewski;Diakowska;Strutyńska-Karpińska;Wojtczak;Domosławski;Balcerzak
通讯作者：
Kaliszewski;Diakowska;Strutyńska-Karpińska;Wojtczak;Domosławski;Balcerzak
影响因子：
6.6
作者：
Niederle, Martin B.;Scheuba, Christian;Niederle, Bruno
通讯作者：
Niederle, Bruno
影响因子：
6.6
作者：
Vierhapper, H;Niederle, B;Baumgartner-Parzer, S
通讯作者：
Baumgartner-Parzer, S