Rapid determination of surfactant critical micelle concentrations using pressure-driven flow with capillary electrophoresis instrumentation.

Rapid determination of surfactant critical micelle concentrations using pressure-driven flow with capillary electrophoresis instrumentation.
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使用毛细管电泳仪器的压力驱动流快速测定表面活性剂临界胶束浓度。

DOI:
10.1016/j.chroma.2009.09.026
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发表时间:
2009
期刊:
Journal of chromatography. A
影响因子:
--
通讯作者:
Stalcup,AM
Stalcup,AM
中科院分区:
--
文献类型:
--
作者:
Stanley,FE;Warner,AM;Schneiderman,E;Stalcup,AM

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这项工作展示了一种新颖、方便的利用毛细管电泳 (CE) 仪器来测定临界胶束浓度 (CMC) 的方法。通过流体动力迫使分析物流向检测器来监测不同表面活性剂浓度范围内的溶液粘度差异。当达到表面活性剂的 CMC 值时,观察到迁移时间发生巨大变化。测定了四种常用阴离子表面活性剂的 CMC 值——十二烷基硫酸钠:8.1mM;辛酸钠:300mM;癸酸钠:86mM;月桂酸钠:30mM;并发现与文献中先前报道的值非常一致。然后将该技术应用于表征不太清楚的非离子表面活性剂聚(氧乙烯)8肉豆蔻基醚(CMC~9M)、聚(氧乙烯)8癸基醚(CMC~0.95mM)和聚(氧乙烯)4月桂基醚。
This work demonstrates a novel, convenient utilization of capillary electrophoresis (CE) instrumentation for the determination of critical micelle concentrations (CMCs). Solution viscosity differences across a range of surfactant concentrations were monitored by hydrodynamically forcing an analyte towards the detector. Upon reaching the surfactant's CMC value, migration times were observed to change drastically. CMC values for four commonly employed anionic surfactants were determined—sodium dodecyl sulfate: 8.1mM; sodium caprylate: 300mM; sodium decanoate: 86mM; sodium laurate: 30mM; and found to be in excellent agreement with values previously reported in the literature. The technique was then applied to the less well-characterized nonionic surfactants poly(oxyethylene) 8 myristyl ether (CMC∼9M), poly(oxyethylene) 8 decyl ether (CMC∼0.95mM) and poly(oxyethylene) 4 lauryl ether.
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