Plant virus expression vector development: new perspectives.

Plant virus expression vector development: new perspectives.
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DOI:
10.1155/2014/785382
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发表时间:
2014
影响因子:
--
通讯作者:
Hefferon K
Hefferon K
中科院分区:
生物学3区
文献类型:
--
作者:
Hefferon K

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近年来,植物制成的生物制剂因其在帮助发展中国家难以获得现代医学的人方面的潜力而引起了人们的广泛关注。其他用途,如储存预防大流行性传染病的疫苗或潜在的生物战剂,也在调查之中。植物病毒表达载体代表了一种能够在非常短的时间内生产高水平药物蛋白的技术。研究和开发的最新进展带来了上级病毒表达系统的产生,该系统可以以有效和成本有效的方式容易地递送到宿主植物。本文介绍了植物病毒表达系统的最新创新及其在植物生物制品生产中的应用。
Plant made biologics have elicited much attention over recent years for their potential in assisting those in developing countries who have poor access to modern medicine. Additional applications such as the stockpiling of vaccines against pandemic infectious diseases or potential biological warfare agents are also under investigation. Plant virus expression vectors represent a technology that enables high levels of pharmaceutical proteins to be produced in a very short period of time. Recent advances in research and development have brought about the generation of superior virus expression systems which can be readily delivered to the host plant in a manner that is both efficient and cost effective. This review presents recent innovations in plant virus expression systems and their uses for producing biologics from plants.
通过复制和非复制载体在植物中快速瞬时生产产生高质量的功能性抗 HIV 抗体。
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