Contrast-enhanced ultrasound for the assessment of placental development and function.

Contrast-enhanced ultrasound for the assessment of placental development and function.
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DOI:
10.2144/btn-2020-0069
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发表时间:
2020-11
期刊:
影响因子:
2.7
通讯作者:
Frias AE
Frias AE
中科院分区:
工程技术4区
文献类型:
--
作者:
Roberts VH;Frias AE

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在超声过程中使用造影剂作为信号增强剂,提高了该技术在医学成像中的可视化和诊断效用。虽然在许多学科中广泛使用,但造影剂超声并没有在产科中常规应用,这主要是由于孕妇用药的安全性问题以及解决这一问题的研究数量有限。本文综述了微泡的特点,使其有利于血池增强和实时成像的量化。本文详细介绍了妊娠动物模型研究和安全性评估的文献,并讨论了对比增强超声提供临床相关数据的潜力,有助于我们了解胎盘早期发育和胎盘功能障碍的检测。
The use of contrast agents as signal enhancers during ultrasound improves visualization and the diagnostic utility of this technology in medical imaging. Although widely used in many disciplines, contrast ultrasound is not routinely implemented in obstetrics, largely due to safety concerns of administered agents for pregnant women and the limited number of studies that address this issue. Here the microbubble characteristics that make them beneficial for enhancement of the blood pool and the quantification of real-time imaging are reviewed. Literature from pregnant animal model studies and safety assessments are detailed, and the potential for contrast-enhanced ultrasound to provide clinically relevant data and benefit our understanding of early placental development and detection of placental dysfunction is discussed.
DOI: 10.1007/s12350-013-9785-0
发表时间: 2013-12
影响因子: 2.4
作者:
Lindner, Jonathan R.;Sinusas, Albert
通讯作者: Sinusas, Albert