Chemical shift-induced phase errors in phase-contrast MRI.
Chemical shift-induced phase errors in phase-contrast MRI.
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DOI：
10.1002/mrm.24262
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发表时间：
2013-02
影响因子：
3.3
通讯作者：
Ennis, Daniel B.
中科院分区：
文献类型：
--
作者：
Middione, Matthew J.;Ennis, Daniel B.
相位对比磁共振成像（PC-MRI）受到许多错误来源的影响，这降低了对报告措施的临床信心。这项工作概述了固定的血管周围脂肪如何通过计算模拟、体外和体内实验来传递显著的化学位移诱导PC-MRI测量误差。这种化学位移误差在相位差处理中不减，但可以通过适当的参数选择最小化。化学位移引起的相位误差很大程度上取决于接收器带宽（BW）和TE。理论和体内对有和没有血管周围脂肪的血管之间净前流最大差异的比较表明，通过使用高体重（814 Hz/px）和同相TE (HBW-TEIN)，化学转移的血管周围脂肪的影响最小。在健康志愿者（N=10）中，与低BW （401 Hz/px）和中期TE相比，HBW-TEIN显着改善了患者体内净前流一致性，这表明显著降低了测量偏差和升主动脉（1.8±0.5 mL vs. 6.4±2.8 mL， P=0.01）、肺动脉主干（2.0±0.9 mL vs. 11.9±5.8 mL， P=0.04）、左肺动脉（1.3±0.9 mL vs. 5.4±2.5 mL， P=0.003）和所有血管（1.7±0.8 mL vs. 7.2±4.4 mL， P=0.001）的一致性限。
Phase contrast magnetic resonance imaging (PC-MRI) is subject to numerous sources of error, which decrease clinical confidence in the reported measures. This work outlines how stationary perivascular fat can impart a significant chemical shift induced PC-MRI measurement error using computational simulations, in vitro, and in vivo experiments. This chemical shift error does not subtract in phase difference processing, but can be minimized with proper parameter selection. The chemical shift induced phase errors largely depend on both the receiver bandwidth (BW) and the TE. Both theory and an in vivo comparison of the maximum difference in net forward flow between vessels with and without perivascular fat indicated that the effects of chemically shifted perivascular fat are minimized by the use of high BW (814 Hz/px) and an in-phase TE (HBW-TEIN). In healthy volunteers (N=10) HBW-TEIN significantly improves intrapatient net forward flow agreement compared to low BW (401 Hz/px) and a mid-phase TE as indicated by significantly decreased measurement biases and limits of agreement for the ascending aorta (1.8±0.5 mL vs. 6.4±2.8 mL, P=0.01), main pulmonary artery (2.0±0.9 mL vs. 11.9±5.8 mL, P=0.04), the left pulmonary artery (1.3±0.9 mL vs. 5.4±2.5 mL, P=0.003), and all vessels (1.7±0.8 mL vs. 7.2±4.4 mL, P=0.001).
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影响因子：
1.3
作者：
FIRMIN, DN;NAYLER, GL;LONGMORE, DB
通讯作者：
LONGMORE, DB
影响因子：
3.3
作者：
Moriguchi, H;Lewin, JS;Duerk, JL
通讯作者：
Duerk, JL
影响因子：
3.3
作者：
FERRIGNO, M;HICKEY, DD;LUNDGREN, CEG
通讯作者：
LUNDGREN, CEG
影响因子：
3.3
作者：
MEYER, CH;PAULY, JM;NISHIMURA, DG
通讯作者：
NISHIMURA, DG
DOI：
10.1186/1532-429x-12-11
发表时间：
2010-03-05
期刊：
Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance
影响因子：
--
作者：
Holland BJ;Printz BF;Lai WW
通讯作者：
Lai WW