Completeness and concordancy of WHO grade assignment for brain and central nervous system tumors in the United States, 2004-2011.
Completeness and concordancy of WHO grade assignment for brain and central nervous system tumors in the United States, 2004-2011.
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DOI：
10.1007/s11060-015-1775-4
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发表时间：
2015-05
影响因子：
3.9
通讯作者：
Barnholtz-Sloan, Jill S.
中科院分区：
文献类型：
--
作者：
Lym, Ryan L.;Ostrom, Quinn T.;Kruchko, Carol;Couce, Marta;Brat, Daniel J.;Louis, David N.;Barnholtz-Sloan, Jill S.
关键词：
根据世界卫生组织 (WHO) 的计划，中枢神经系统 (CNS) 肿瘤出于临床和研究目的进行分类和分级，该计划按组织学类型和预测的生物学行为对肿瘤进行分类。然而，尽管在癌症登记中收集了 WHO 等级，但病理报告中的 WHO 等级报告并不一致。我们研究了 2004 年至 2011 年间原发性 CNS 肿瘤 WHO 分级收集的完整性、一致性和年度趋势。分析了监测、流行病学和最终结果计划的数据，以了解 2004 年至 2011 年间组织学诊断的原发性 CNS 肿瘤病例中具有一致记录的 WHO 分级的百分比。通过年度百分比变化 (APC) 和 95% 置信区间计算年度趋势(95% CI)。 WHO 等级收集的完整性和一致性因组织学类型和年份的不同而存在显着差异。从 2004 年到 2011 年，有记录的 WHO 分级的病例百分比显着增加：2004 年，39.0% 的病例有记录的 WHO 分级，而 2011 年，77.5% 的病例有记录的分级（APC，10.3；95% CI：9.0，11.5）。在记录有 WHO 分级的病例中，一致分级的百分比从 2004 年的 89.1% 显着增加到 2007 年的 93.7%（APC，1.8；95% CI：1.0，2.6），并且这些值随组织学类型的不同而变化。所有组织学的一个共同趋势是具有记录的 WHO 分级的病例百分比显着增加。癌症登记员收集的报告中枢神经系统肿瘤中，很大一部分没有记录 WHO 分级，而一小部分分级不一致。随着时间的推移，年级数据收集的完整性和一致性不断提高。进一步改进这一变量的收集对于中枢神经系统肿瘤的临床护理和流行病学监测至关重要。
Central nervous system (CNS) tumors are categorized and graded for clinical and research purposes according to the World Health Organization (WHO) scheme which segregates tumors by histological type and predicted biological behavior. However, reporting of WHO grade in pathological reports is inconsistent despite its collection in cancer registration. We studied the completeness, concordancy, and yearly trends in the collection of WHO grade for primary CNS tumors between 2004 and 2011. Data from the Surveillance, Epidemiology and End Results program were analyzed for the percentage of histologically diagnosed primary CNS tumor cases with concordantly documented WHO grades between 2004 and 2011. Yearly trends were calculated with annual percentage changes (APC) and 95 % confidence intervals (95 % CI). Completeness and concordancy of the collection of WHO grade varied significantly by histological type and year. The percentage of cases with documented WHO grade increased significantly from 2004 to 2011: 39.0 % of cases in 2004 had documented WHO grade, while 77.5 % of cases had documented grade in 2011 (APC, 10.3; 95 % CI: 9.0, 11.5). Among cases with documented WHO grade, the percentage graded concordantly increased significantly from 89.1 % in 2004 to 93.7 % in 2007 (APC, 1.8; 95 % CI: 1.0, 2.6) and these values varied over time by histological type. One common trend among all histologies was a significant increase in the percentage of cases with documented WHO grade. A sizeable proportion of reported CNS tumors collected by cancer registrars have undocumented WHO grade, while a much smaller proportion are graded discordantly. Data collection on grade has improved in completeness and concordancy over time. Efforts to further improve collection of this variable are essential for clinical care and the epidemiological surveillance of CNS tumors.
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国际神经病理学协会 - 哈勒姆神经系统肿瘤分类和分级共识指南。
DOI：
10.1111/bpa.12171
发表时间：
2014-09
期刊：
Brain pathology (Zurich, Switzerland)
影响因子：
--
作者：
Louis DN;Perry A;Burger P;Ellison DW;Reifenberger G;von Deimling A;Aldape K;Brat D;Collins VP;Eberhart C;Figarella-Branger D;Fuller GN;Giangaspero F;Giannini C;Hawkins C;Kleihues P;Korshunov A;Kros JM;Beatriz Lopes M;Ng HK;Ohgaki H;Paulus W;Pietsch T;Rosenblum M;Rushing E;Soylemezoglu F;Wiestler O;Wesseling P;International Society Of Neuropathology--Haarlem
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International Society Of Neuropathology--Haarlem
影响因子：
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通讯作者：
Dumont, L. J.
影响因子：
5
作者：
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DOI：
10.1016/j.ijrobp.2008.08.018
发表时间：
2009-06-01
影响因子：
7
作者：
Rosenberg, Lewis A.;Prayson, Richard A.;Suh, John H.
通讯作者：
Suh, John H.
影响因子：
15.9
作者：
Ostrom, Quinn T.;Gittleman, Haley;Barnholtz-Sloan, Jill
通讯作者：
Barnholtz-Sloan, Jill