The Back Pain Consortium (BACPAC) Research Program: Structure, Research Priorities, and Methods.
The Back Pain Consortium (BACPAC) Research Program: Structure, Research Priorities, and Methods.
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DOI：
10.1093/pm/pnac202
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发表时间：
2023-08-04
期刊：
影响因子：
3.1
通讯作者：
LaVange, Lisa
中科院分区：
文献类型：
--
作者：
Mauck, Matthew C.;Lotz, Jeffrey;Psioda, Matthew A.;Carey, Timothy S.;Clauw, Daniel J.;Majumdar, Sharmila;Marras, William S.;Vo, Nam;Aylward, Ayleen;Hoffmeyer, Anna;Zheng, Patricia;Ivanova, Anastasia;McCumber, Micah;Carson, Christiane;Anstrom, Kevin J.;Bowden, Anton E.;Dalton, Diane;Derr, Leslie;Dufour, Jonathan;Fields, Aaron J.;Fritz, Julie;Hassett, Afton L.;Harte, Steven E.;Hue, Trisha F.;Krug, Roland;Loggia, Marco L.;Mageswaran, Prasath;McLean, Samuel A.;Mitchell, Ulrike H.;O'Neill, Conor;Pedoia, Valentina;Quirk, David Adam;Rhon, Daniel, I;Rieke, Viola;Shah, Lubdha;Sowa, Gwendolyn;Spiegel, Brennan;Wasan, Ajay D.;Wey, Hsiao-Ying (Monica);LaVange, Lisa
关键词：
2019年，国民健康访谈调查发现，近59%的成年人在过去3个 月中报告部分、最多或每天疼痛，39%的人报告背痛，使背痛成为最普遍的疼痛来源，也是成年人中的一个重要问题。通常，确定背痛的直接、可治疗的原因是具有挑战性的，特别是因为它通常被归因于涉及生物、心理和社会因素的复杂的、多方面的问题。由于慢性下腰痛(CLBP)的真正原因难以治疗，cLBP患者过度依赖阿片类止痛药，这与阿片类药物使用障碍的患病率增加和死亡风险增加有关。为了应对阿片类药物相关死亡人数的上升，美国国立卫生研究院(NIH)发起了帮助结束长期成瘾SM(Hear)倡议，其目标是解决阿片类药物使用障碍的原因和治疗，同时寻求更好地了解、诊断和治疗慢性疼痛。NIH背痛联盟(BACPAC)研究计划是由14个资助实体组成的网络，作为Hear倡议的一部分，以帮助解决围绕cLBP诊断和治疗的限制。本文概述了BACPAC研究计划的目标和总体结构，并描述了整个联盟的协调努力，确定了其研究议程，并开发了一个利用网络优势的合作项目。这篇论文的目的是为其他致力于推进疼痛相关科学的联盟提供蓝图。
In 2019, the National Health Interview survey found that nearly 59% of adults reported pain some, most, or every day in the past 3 months, with 39% reporting back pain, making back pain the most prevalent source of pain, and a significant issue among adults. Often, identifying a direct, treatable cause for back pain is challenging, especially as it is often attributed to complex, multifaceted issues involving biological, psychological, and social components. Due to the difficulty in treating the true cause of chronic low back pain (cLBP), an over-reliance on opioid pain medications among cLBP patients has developed, which is associated with increased prevalence of opioid use disorder and increased risk of death. To combat the rise of opioid-related deaths, the National Institutes of Health (NIH) initiated the Helping to End Addiction Long-TermSM (HEAL) initiative, whose goal is to address the causes and treatment of opioid use disorder while also seeking to better understand, diagnose, and treat chronic pain. The NIH Back Pain Consortium (BACPAC) Research Program, a network of 14 funded entities, was launched as a part of the HEAL initiative to help address limitations surrounding the diagnosis and treatment of cLBP. This paper provides an overview of the BACPAC research program’s goals and overall structure, and describes the harmonization efforts across the consortium, define its research agenda, and develop a collaborative project which utilizes the strengths of the network. The purpose of this paper is to serve as a blueprint for other consortia tasked with the advancement of pain related science.
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影响因子：
120.7
作者：
Dieleman, Joseph L.;Cao, Jackie;Murray, Christopher J. L.
通讯作者：
Murray, Christopher J. L.
影响因子：
5
作者：
Quan, Hude;Li, Bing;Sundararajan, Vijaya
通讯作者：
Sundararajan, Vijaya
影响因子：
7.2
作者：
CHARLSON, M;SZATROWSKI, TP;GOLD, J
通讯作者：
GOLD, J
影响因子：
2.9
作者：
Birckhead B;Eberlein S;Alvarez G;Gale R;Dupuy T;Makaroff K;Fuller G;Liu X;Yu KS;Black JT;Ishimori M;Venuturupalli S;Tu J;Norris T;Tighiouart M;Ross L;McKelvey K;Vrahas M;Danovitch I;Spiegel B
通讯作者：
Spiegel B
DOI：
10.1016/j.jpain.2019.05.007
发表时间：
2020-01
期刊：
The journal of pain
影响因子：
--
作者：
Schrepf A;Phan V;Clemens JQ;Maixner W;Hanauer D;Williams DA
通讯作者：
Williams DA