Menstrual Cycle Phase Modulates Auditory-Motor Integration for Vocal Pitch Regulation.
Menstrual Cycle Phase Modulates Auditory-Motor Integration for Vocal Pitch Regulation.
复制标题
月经周期相位调节听觉运动整合以调节音调
DOI：
10.3389/fnins.2016.00600
复制
发表时间：
2016
影响因子：
4.3
通讯作者：
Liu H
中科院分区：
文献类型：
--
作者：
Zhu X;Niu Y;Li W;Zhang Z;Liu P;Chen X;Liu H
在成年女性中，先前的工作已经证明，听觉功能和发声运动行为的变化可能伴随着性腺类固醇的变化。然而，关于性腺类固醇对人类语音控制的神经-运动整合的影响知之甚少。本事件相关电位（ERP）的研究试图检查性腺类固醇和听觉反馈为基础的音调调节整个月经周期之间的相互作用。在月经周期的月经期、卵泡期和黄体期，参与者在听到自己的声音时产生了持续的元音。在所有三个阶段进行测量的声乐和皮质反应的音调反馈扰动和评估的雌二醇和孕酮水平。行为结果表明，月经期（当雌二醇水平低）与更大幅度的声音反应比卵泡期和黄体期（当雌二醇水平高）。此外，有一个显着的负相关性之间的声音反应的幅度和雌二醇水平。在皮质水平，ERP P2反应较小，在黄体期（当孕酮水平高）比月经和卵泡期（当孕酮水平低）。这些研究结果显示了神经行为学证据的调制在月经周期的音高调节的神经运动整合，并提供了重要的见解的神经机制和功能结果的性腺类固醇激素的影响，在成年女性的言语运动控制。
In adult females, previous work has demonstrated that changes in auditory function and vocal motor behaviors may accompany changes in gonadal steroids. Less is known, however, about the influence of gonadal steroids on auditory-motor integration for voice control in humans. The present event-related potential (ERP) study sought to examine the interaction between gonadal steroids and auditory feedback-based vocal pitch regulation across the menstrual cycle. Participants produced sustained vowels while hearing their voice unexpectedly pitch-shifted during the menstrual, follicular, and luteal phases of the menstrual cycle. Measurement of vocal and cortical responses to pitch feedback perturbations and assessment of estradiol and progesterone levels were performed in all three phases. The behavioral results showed that the menstrual phase (when estradiol levels are low) as associated with larger magnitudes of vocal responses than the follicular and luteal phases (when estradiol levels are high). Furthermore, there was a significant negative correlation between the magnitudes of vocal responses and estradiol levels. At the cortical level, ERP P2 responses were smaller during the luteal phase (when progesterone levels were high) than the menstrual and follicular phases (when progesterone levels were low). These findings show neurobehavioral evidence for the modulation of auditory-motor integration for vocal pitch regulation across the menstrual cycle, and provide important insights into the neural mechanisms and functional outcomes of gonadal steroids' influence on speech motor control in adult women.
登录
查看更多内容
注意力调节语音控制中音调反馈误差的皮层处理
影响因子：
4.6
作者：
Hu H;Liu Y;Guo Z;Li W;Liu P;Chen S;Liu H
通讯作者：
Liu H
影响因子：
5.7
作者：
Behroozmand R;Shebek R;Hansen DR;Oya H;Robin DA;Howard MA 3rd;Greenlee JD
通讯作者：
Greenlee JD
影响因子：
2.4
作者：
Burnett, TA;Freedland, MB;Hain, TC
通讯作者：
Hain, TC
影响因子：
3.2
作者：
Behroozmand R;Liu H;Larson CR
通讯作者：
Larson CR
DOI：
10.1073/pnas.0606891103
发表时间：
2006-09-19
影响因子：
11.1
作者：
Guimaraes, Patricia;Frisina, Susan T.;Frisina, Robert D.
通讯作者：
Frisina, Robert D.