Selective autophagy: xenophagy.
Selective autophagy: xenophagy.
复制标题
选择性自噬:异种。
DOI:
10.1016/j.ymeth.2014.12.005
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发表时间:
2015-03
期刊:
影响因子:
4.8
通讯作者:
Mysorekar, Indira U.
中科院分区:
文献类型:
--
作者:
Bauckman, Kyle A.;Owusu-Boaitey, Nana;Mysorekar, Indira U.
Xenophagy is an autophagic phenomenon that specifically involves pathogens and other non-host entities. Although the understanding of the relationship between autophagosomes and invading organisms has grown significantly in the past decade, the exact steps to confirm xenophagy has been not been thoroughly defined. Here we describe a methodical approach to confirming autophagy, its interaction with bacterial invasion, as well as the specific type of autophagic formation (i.e. autophagosome, autolysosome, phagolysosome). Further, we argue that xenophagy is not limited to pathogen interaction with autophagosome, but also non-microbial entities such as iron.
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DOI:
10.1073/pnas.1210500109
发表时间:
2012-11-13
影响因子:
11.1
作者:
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通讯作者:
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通讯作者:
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