Gianotti-Crosti syndrome caused by acute hepatitis B virus genotype D infection.

Gianotti-Crosti syndrome caused by acute hepatitis B virus genotype D infection.
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Gianotti-Crosti 综合征由 D 基因型急性乙型肝炎病毒感染引起。

DOI:
10.2169/internalmedicine.43.696
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发表时间:
2004
期刊:
影响因子:
1.2
通讯作者:
M. Onji
M. Onji
中科院分区:
医学4区
文献类型:
--
作者:
K. Michitaka;N. Horiike;Yan Chen;T. Duong;I. Konishi;Toshie Mashiba;Yoshio Tokumoto;Y. Hiasa;Yasuhito Tanaka;M. Mizokami;M. Onji

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一个12岁的女孩与Gianotti-Crosti综合征引起的肝炎B病毒(HBV)感染,是因为她的四肢皮疹入院。实验室检查结果显示转氨酶升高、HB表面抗原(HBsAg)阳性和IgM型抗HB核心抗体。出疹和转氨酶水平改善,HBsAg在发病后2个月内转阴。对病毒的分析显示,它是基因组长度为3,182个碱基的D型,HBsAg血清型为ayw 3,这在日本非常罕见。对Gianotti-Crosti综合征与HBV D基因型感染的可能关系进行了讨论。
A 12-year-old girl with Gianotti-Crosti syndrome caused by hepatitis B virus (HBV) infection was admitted due to eruption on her extremities. Laboratory findings revealed elevation of transaminase, positivity for HB surface antigen (HBsAg), and an IgM type anti-HB core. The eruption and level of transaminase improved, and HBsAg became negative within 2 months of onset. Analysis of the virus revealed it to be genotype D with a genomic length of 3,182 bases and the HBsAg serotype was ayw3, which is very rare in Japan. The possible relationship between Gianotti-Crosti syndrome and HBV genotype D infection is discussed.
DOI: 10.1053/jhep.2001.27221
发表时间: 2001-09-01
期刊: HEPATOLOGY
影响因子: 13.5
作者:
Orito, E;Ichida, T;Mizokami, M
通讯作者: Mizokami, M