Backbone (1)H, (13)C, and (15)N resonance assignments of guanylyl cyclase activating protein-1, GCAP1.

Backbone (1)H, (13)C, and (15)N resonance assignments of guanylyl cyclase activating protein-1, GCAP1.
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DOI:
10.1007/s12104-012-9373-2
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发表时间:
2013-04
影响因子:
0.9
通讯作者:
Ames JB
Ames JB
中科院分区:
生物学4区
文献类型:
--
作者:
Lim S;Peshenko IV;Dizhoor AM;Ames JB

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观酰基环化酶激活蛋白1 (GCAP1)是钙调蛋白超家族中神经元钙传感器亚类的成员,赋予Ca2+依赖性的视网膜观酰基环化酶激活,调节视觉光反应。GCAP1基因与视网膜退行性疾病有关。我们报道了Ca2+饱和GCAP1 (BMRB号)的骨架核磁共振化学位移分配。18026)。
Guanylyl cyclase activating protein 1 (GCAP1), a member of the neuronal calcium sensor subclass of the calmodulin superfamily, confers Ca2+-dependent activation of retinal guanylyl cyclase that regulates the visual light response. GCAP1 is genetically linked to retinal degenerative diseases. We report backbone NMR chemical shift assignments of Ca2+-saturated GCAP1 (BMRB no. 18026).
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