Atrial natriuretic polypeptide in atria and plasma in experimental hyperthyroidism and hypothyroidism.
Atrial natriuretic polypeptide in atria and plasma in experimental hyperthyroidism and hypothyroidism.
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实验性甲状腺功能亢进症和甲状腺功能减退症中心房和血浆中的心钠素。
DOI：
10.1016/0006-291x(86)90544-9
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发表时间：
1986
影响因子：
3.1
通讯作者：
T. Takeda
中科院分区：
文献类型：
--
作者：
M. Kohno;K. Takaori;T. Matsuura;K. Murakawa;Y. Kanayama;T. Takeda
为探讨甲状腺激素对心房钠尿肽（ANP）释放的影响，测定了实验性甲状腺功能亢进（甲亢）和甲状腺功能减退（甲减）大鼠心房和血浆中ANP的含量。甲亢大鼠血浆ANP明显高于正常大鼠（P<0.05），甲低大鼠血浆ANP明显低于正常大鼠（P<0.05）。甲亢大鼠心房心钠素含量和浓度明显低于甲低大鼠（P<0.01）。血浆ANP与心房ANP浓度呈负相关（n=15，r=-0.60，p<0.01）。结果表明，在甲状腺功能亢进症心房心钠素的全身释放增加和甲状腺功能减退症的全身释放减少。
To investigate the involvement of thyroid hormone on the release of atrial natriuretic polypeptide (ANP), we have measured immunoreactive ANP in the atria and plasma of experimental hyperthyroid and hypothyroid rats. Plasma ANP was higher (p<0.05) in hyperthyroid rats and was lower (p<0.05) in hypothyroid rats than in euthyroid rats. ANP content and concentration in the atria were lower (p<0.01) in hyperthyroid rats than in hypothyroid rats. An inverse correlation was found between the plasma ANP and ANP concentration in the atria (n=15, r=−0.60, p<0.01). The results indicate an increased systemic release of ANP from the atria in hyperthyroidism and a decreased systemic release in hypothyroidism.
大鼠下丘脑、心房和血浆中的心房钠尿因子：通过特异性放射免疫测定法测定。
DOI：
10.1016/0006-291x(84)91606-1
发表时间：
1984
影响因子：
3.1
作者：
Tanaka,I;Misono,KS;Inagami,T
通讯作者：
Inagami,T