Atrial natriuretic factor in rat hypothalamus, atria and plasma: determination by specific radioimmunoassay.

Atrial natriuretic factor in rat hypothalamus, atria and plasma: determination by specific radioimmunoassay.
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大鼠下丘脑、心房和血浆中的心房钠尿因子:通过特异性放射免疫测定法测定。

DOI:
10.1016/0006-291x(84)91606-1
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发表时间:
1984
影响因子:
3.1
通讯作者:
Inagami,T
Inagami,T
中科院分区:
生物学4区
文献类型:
--
作者:
Tanaka,I;Misono,KS;Inagami,T

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开发了一种快速且可重复的大鼠心房钠尿因子(ANF)-IV 放射免疫测定方法。该方法也适用于人心房肽。在大鼠下丘脑(5.03 pmoles/g 组织)、右心房(86.8 pmoles/mg 组织)和左心房(52.5 pmoles/mg 组织)和血浆(156 fmoles/ml)中检测到 ANF。高盐摄入后,心房和血浆中的免疫反应性 ANF 显着增加,而下丘脑中的免疫反应性 ANF 显着减少。凝胶色谱显示心房和下丘脑中存在高分子量和低分子量 ANF,而血浆中仅发现低分子量形式。
A rapid and reproducible radioimmunoassay method was developed for rat atrial natriuretic factor (ANF)-IV. The method is also applicable to human atrial peptide. ANF was detected in rat hypothalamus (5.03 pmoles/g tissue), right (86.8 pmoles/mg tissue) and left atria (52.5 pmoles/mg tissue), and plasma (156 fmoles/ml). After high salt intake immunoreactive ANF in atria and plasma increased significantly, while a significant decrease was observed in hypothalamus. Gel chromatography revealed high and low molecular weight ANF in atria and hypothalamus while only a low molecular weight form was found in plasma.
心房肽原的序列:生物活性心房肽的前体。
DOI: 10.1016/0006-291x(84)90749-6
发表时间: 1984
影响因子: 3.1
作者:
D. Geller;M. Currie;N. Siegel;K. Fok;S. Adams;P. Needleman
通讯作者: P. Needleman
心房原钠舒张素:利尿钠因子和心脏舒张素的前体
DOI: 10.1016/0014-5793(84)80878-9
发表时间: 1984
期刊: FEBS Letters
影响因子: 3.5
作者:
C. Lazure;N. Seidah;M. Chrétien;G. Thibault;R. Garcia;M. Cantin;J. Genest
通讯作者: J. Genest
DOI: 10.1016/s0006-291x(84)80279-x
发表时间: 1984-03
影响因子: 3.1
作者:
K. Misono;H. Fukumi;R. Grammer;T. Inagami
通讯作者: K. Misono;H. Fukumi;R. Grammer;T. Inagami
DOI: 10.1016/s0006-291x(84)80074-1
发表时间: 1984-01-01
影响因子: 3.1
作者:
GUTKOWSKA, J;THIBAULT, G;GENEST, J
通讯作者: GENEST, J
DOI: 10.1038/194495a0
发表时间: 1962-01-01
期刊: NATURE
影响因子: 64.8
作者:
HUNTER, WM;GREENWOOD, FC
通讯作者: GREENWOOD, FC