The contribution of animal models to the understanding of the host range and virulence of influenza A viruses.

The contribution of animal models to the understanding of the host range and virulence of influenza A viruses.
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DOI:
10.1016/j.micinf.2011.01.014
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发表时间:
2011-05
影响因子:
5.8
通讯作者:
Subbarao K
Subbarao K
中科院分区:
医学3区
文献类型:
--
作者:
O'Donnell CD;Subbarao K

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自1933年首次使用雪貂进行甲型流感病毒的初步分离以来,动物模型一直是流感研究的关键。本文综述了小鼠、雪貂和非人灵长类动物对流感病毒宿主范围和致病性研究的贡献。
Since ferrets were first used in 1933 during the initial isolation of influenza A viruses, animal models have been critical for influenza research. The following review discusses the contribution of mice, ferrets and non-human primates to the study of influenza virus host-range and pathogenicity.
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