Multiple Mechanisms Regulate Eukaryotic Cytochrome C Oxidase.
Multiple Mechanisms Regulate Eukaryotic Cytochrome C Oxidase.
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作者：
Ramzan R;Kadenbach B;Vogt S
Cytochrome c oxidase (COX), the rate-limiting enzyme of mitochondrial respiration, is regulated by various mechanisms. Its regulation by ATP (adenosine triphosphate) appears of particular importance, since it evolved early during evolution and is still found in cyanobacteria, but not in other bacteria. Therefore the “allosteric ATP inhibition of COX” is described here in more detail. Most regulatory properties of COX are related to “supernumerary” subunits, which are largely absent in bacterial COX. The “allosteric ATP inhibition of COX” was also recently described in intact isolated rat heart mitochondria.
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DOI：
10.1111/j.1432-1033.1993.tb18342.x
发表时间：
1993-11-01
期刊：
EUROPEAN JOURNAL OF BIOCHEMISTRY
影响因子：
--
作者：
BONNE, G;SEIBEL, P;KADENBACH, B
通讯作者：
KADENBACH, B
影响因子：
64.5
作者：
Fukuda, Ryo;Zhang, Huafeng;Semenza, Gregg L.
通讯作者：
Semenza, Gregg L.
影响因子：
4.4
作者：
Endou, Masahiro;Yoshida, Kaito;Kurihara, Yasuyuki
通讯作者：
Kurihara, Yasuyuki
影响因子：
4.6
作者：
Alge, D;Wastyn, M;Peschek, GA
通讯作者：
Peschek, GA
影响因子：
20.1
作者：
Forrester SJ;Kikuchi DS;Hernandes MS;Xu Q;Griendling KK
通讯作者：
Griendling KK