Subclinical disability in valued life activities among individuals with rheumatoid arthritis.
Subclinical disability in valued life activities among individuals with rheumatoid arthritis.
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DOI：
10.1002/art.24110
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发表时间：
2008-10-15
影响因子：
--
通讯作者：
Yelin, Edward
中科院分区：
文献类型：
--
作者：
Katz, Patricia;Morris, Anne;Yelin, Edward
“亚临床残疾”，即需要改变任务表现或频率而不报告任务困难，已被确定为残疾连续体沿着一个阶段。我们估计类风湿性关节炎（RA）患者中有价值生活活动（VLA）亚临床残疾的患病率，确定VLA亚临床残疾患者的特征，并估计VLA亚临床残疾预测功能后期减退的能力。数据来自三年的纵向小组研究的个人与RA，每年进行结构化电话采访（n=508年1，442年3）。受访者对VLA的难度进行评级，然后报告他们是否使用了四种行为修改（限制，额外时间，帮助，设备）中的任何一种。每个VLA的亚临床残疾定义为未报告使用任何改良的困难。多元回归分析确定了第1年亚临床残疾的预测因素，以及第1年亚临床残疾在第1年至第3年明显残疾发展中的作用。近四分之三的人在第1年至少有一个VLA表现出亚临床残疾。RA持续时间与亚临床残疾一致相关。基线时亚临床残疾的个体在前瞻性两年期内更有可能经历功能限制（OR=1.09 [1.01，1.18]）和VLA残疾（总VLA：OR=1.14 [1.06，1.23]）的增加。亚临床残疾可能是处于残疾过渡阶段的个人的一个有价值的标志，这些人特别容易接受干预，使他们能够保持功能。
“Subclinical disability,” the need for modifications in task performance or frequency without reporting difficulty in the task, has been identified as a stage along the disability continuum. We estimate the prevalence of subclinical disability in valued life activities (VLAs) among individuals with rheumatoid arthritis (RA), identify characteristics of individuals with VLA subclinical disability, and estimate the ability of VLA subclinical disability to predict later decrements in functioning. Data were from three years of a longitudinal panel study of individuals with RA, for which annual structured telephone interviews are conducted (n=508 in year 1, 442 in year 3). Respondents rated difficulty in VLAs and then reported whether they used any of four behavioral modifications (limitations, extra time, help, equipment) for each. Subclinical disability was defined for each VLA as no reported difficulty with use of any modification. Multiple regression analyses identified predictors of subclinical disability in year 1, and the role of year 1 subclinical disability in development of overt disability between year 1 and year 3. Almost three quarters exhibited subclinical disability in at least one VLA in year 1. Duration of RA was consistently associated with subclinical disbility. Individuals with subclinical disability at baseline were significantly more likely to experience increases in functional limitations (OR=1.09 [1.01,1.18]) and VLA disability (Total VLA: OR=1.14 [1.06,1.23]) over a prospective two-year period. Subclinical disability may be a valuable marker of individuals in a disability transition phase who are particularly susceptible to intervention to enable them to maintain functioning.
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影响因子：
5.4
作者：
Agree, EM
通讯作者：
Agree, EM
DOI：
10.1002/art.21580
发表时间：
2005-12-15
期刊：
ARTHRITIS & RHEUMATISM-ARTHRITIS CARE & RESEARCH
影响因子：
--
作者：
Katz, PP
通讯作者：
Katz, PP
影响因子：
5.4
作者：
VERBRUGGE, LM;JETTE, AM
通讯作者：
JETTE, AM
DOI：
10.1016/j.apmr.2007.06.016
发表时间：
2007-09-01
影响因子：
4.3
作者：
Maenty, Minna;Heinonen, Ari;Rantanen, Taina
通讯作者：
Rantanen, Taina
影响因子：
3.7
作者：
Gignac, MAM;Cott, C;Badley, EM
通讯作者：
Badley, EM