Dissection of fission yeast microtubule associating protein p93Dis1: regions implicated in regulated localization and microtubule interaction
Dissection of fission yeast microtubule associating protein p93Dis1: regions implicated in regulated localization and microtubule interaction
复制标题
裂殖酵母微管关联蛋白 p93Dis1 的解剖：涉及调节定位和微管相互作用的区域
作者：
Y. Nakaseko;K. Nabeshima;Kazuhisa Kinoshita;M. Yanagida
背景：裂殖酵母微管相关蛋白（MAP）p93 Dis1在姐妹染色单体分离中起作用：Dis1突变体不能分离染色体，纺锤体延长但不破坏细胞周期蛋白。 p93 Dis1定位于间期细胞质中的沿着微管，但在进入有丝分裂时转移到纺锤体极体（SPB）和纺锤体微管。在这项研究中，p93Dis1的区域进行了解剖，以检查它们的作用。
Background: Fission yeast microtubule associating protein (MAP) p93Dis1 functions for sister chromatid separation: dis1 mutants fail to separate chromosomes, while the spindle elongates but without cyclin destruction. p93Dis1 localizes along microtubules in interphase cytoplasm, but shifts to the spindle pole body (SPB) and spindle microtubules upon the entry into mitosis. In this study, regions of p93Dis1 were dissected to examine their role.
影响因子：
4
作者：
I. Hagan;J. Hyams
通讯作者：
I. Hagan;J. Hyams