Daycare Attendance is Linked to Increased Risk of Respiratory Morbidities in Children Born Preterm with Bronchopulmonary Dysplasia.
Daycare Attendance is Linked to Increased Risk of Respiratory Morbidities in Children Born Preterm with Bronchopulmonary Dysplasia.
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日托出勤率与支气管肺发育不良早产儿呼吸系统疾病风险增加有关
DOI：
10.1016/j.jpeds.2022.06.037
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发表时间：
2022-10
影响因子：
5.1
通讯作者：
Collaco, Joseph M.
中科院分区：
文献类型：
--
作者：
McGrath-Morrow, Sharon A.;Agarwal, Amit;Alexiou, Stamatia;Austin, Eric D.;Fierro, Julie L.;Hayden, Lystra P.;Lai, Khanh;Levin, Jonathan C.;Manimtim, Winston M.;Moore, Paul E.;Rhein, Lawrence M.;Rice, Jessica L.;Sheils, Catherine A.;Tracy, Michael C.;Bansal, Manvi;Baker, Christopher D.;Cristea, A. Ioana;Popova, Antonia P.;Siddaiah, Roopa;Villafranco, Natalie;Nelin, Leif D.;Collaco, Joseph M.
对于支气管肺发育不良（BPD）的婴儿，出生后最初几年的肺生长至关重要，因为BPD在早产时改变了肺泡、气道和血管发育。急性呼吸道疾病可能会在这一关键时期进一步破坏出生后肺部的生长和发育。确定降低呼吸道疾病风险的可改变因素可能有助于改善这些儿童的呼吸结果。我们假设，在日托中心的BPD儿童在生命的前三年会有更多的呼吸系统疾病的医疗保健利用。这是一项回顾性队列研究（n=341），使用标准化工具从不同地理区域的9家BPD专科诊所收集数据。受试者是患有支气管肺发育不良（71%严重）的前早产儿（<34周），需要0-3岁的门诊随访。参加日托的BPD儿童更有可能急诊和全身使用类固醇。与没有日托的儿童相比，三岁以下的日托儿童也更有可能报告呼吸困难，活动受限和使用急救药物。在6-12个月的实际年龄之间参加日托的儿童中发现了更严重的表现。在这项研究中，与未参加日托的儿童相比，参加日托的BPD早产儿更有可能去急诊室就诊，使用全身性类固醇，并有慢性呼吸道症状，这表明日托可能是一个潜在的可改变的风险因素，以尽量减少学龄前BPD儿童的呼吸道发病率。
Postnatal lung growth during the first few years of life is critical for infants with bronchopulmonary dysplasia (BPD) who have altered alveolar, airway, and vascular development in the setting of premature birth. Acute respiratory illnesses may further disrupt postnatal lung growth and development during this crucial period. Identifying modifiable factors that mitigate risk of respiratory illnesses may help improve respiratory outcomes in these children. We hypothesized that children with BPD in daycare would have greater healthcare utilization for respiratory illnesses during the first three years of life. This was a retrospective cohort study (n=341) using data collected from nine BPD specialty clinics from diverse geographic areas, using standardized instruments. Subjects were former preterm infants (<34 weeks) with bronchopulmonary dysplasia (71% severe) requiring outpatient follow-up between 0–3 years of age. Children with BPD attending daycare were more likely to have emergency department visits and systemic steroid usage. Children in daycare up to three years of age were also more likely to report trouble breathing, having activity limitations, and using rescue medications when compared to children not in daycare. More severe manifestations were found in children attending daycare between 6–12 months chronological age. In this study, preterm children with BPD who attend daycare were more likely to visit the emergency department, use systemic steroids and have chronic respiratory symptoms compared to children not in daycare indicating that daycare may be a potential modifiable risk factor to minimize respiratory morbidities in children with BPD during the preschool years.
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影响因子：
3.6
作者：
Chida-Nagai, Ayako;Sato, Hiroki;Takeda, Atsuhito
通讯作者：
Takeda, Atsuhito
影响因子：
4.4
作者：
Moschino, Laura;Carraro, Silvia;Baraldi, Eugenio
通讯作者：
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影响因子：
8
作者：
Chan, Johnny Y. C.;Stern, Debra A.;Martinez, Fernando D.
通讯作者：
Martinez, Fernando D.
影响因子：
3.1
作者：
Collaco JM;Agarwal A;Austin ED;Hayden LP;Lai K;Levin J;Manimtim WM;Moore PE;Sheils CA;Tracy MC;Alexiou S;Baker CD;Cristea AI;Fierro JL;Rhein LM;Villafranco N;Nelin LD;McGrath-Morrow SA
通讯作者：
McGrath-Morrow SA
影响因子：
8
作者：
McGrath-Morrow, Sharon A.;Lee, Grace;Collaco, J. Michael
通讯作者：
Collaco, J. Michael