The Synergistic Effects of Orthokeratology and Atropine in Slowing the Progression of Myopia.
The Synergistic Effects of Orthokeratology and Atropine in Slowing the Progression of Myopia.
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正差异学和阿托品的协同作用在减慢近视的发展方面。
DOI：
10.3390/jcm7090259
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发表时间：
2018-09-07
影响因子：
3.9
通讯作者：
Lin HJ
中科院分区：
文献类型：
--
作者：
Wan L;Wei CC;Chen CS;Chang CY;Lin CJ;Chen JJ;Tien PT;Lin HJ
阿托品和角膜塑形术（OK）都能有效减缓近视的进展。在目前的研究中，我们研究了阿托品和OK镜片对减缓近视进展的联合作用。这项回顾性研究包括84名配戴OK镜片并接受阿托品治疗（OA）的患者和95名仅配戴OK镜片（OK）2年的患者。我们将患者分为低度（<6 D，LM）和高度（≥6 D，HM）近视组，以及两种不同的阿托品浓度（0.125%和0.025%）。与OK 1患者相比，OA 1患者的LM控制显著更好。OA 1组的轴长（24.67 ± 1.53 mm）显著短于OK 1组（24.9 ± 1.98 mm）（p = 0.042）;同样，OA 2组的轴长（24.73 ± 1.53 mm）短于OK 2组（25.01 ± 1.26 mm）（p = 0.031）。对于HM患者，OA 3患者与OK 3患者相比，OA 3组的眼轴长度明显缩短（25.78 ± 1.46）mm（25.93 ± 1.94 mm）（p = 0.021）;同样，OA 4患者（25.86 ± 1.21 mm）短于OK 4患者（26.05 ± 1.57 mm）（p = 0.011）。联合使用阿托品和OK镜是控制近视发展的一种选择。
Atropine and orthokeratology (OK) are both effective in slowing the progression of myopia. In the current study, we studied the combined effects of atropine and OK lenses on slowing the progression of myopia. This retrospective study included 84 patients who wore OK lenses and received atropine treatment (OA) and 95 patients who wore OK lenses alone (OK) for 2 years. We stratified patients into low (<6 D, LM) and high (≥6 D, HM) myopia groups, as well as two different atropine concentrations (0.125% and 0.025%). Significantly better LM control was observed in OA1 patients, compared with OK1 patients. Axial length was significantly shorter in the OA1 group (24.67 ± 1.53 mm) than in the OK1 group (24.9 ± 1.98 mm) (p = 0.042); similarly, it was shorter in the OA2 group (24.73 ± 1.53 mm) than in the OK2 group (25.01 ± 1.26 mm) (p = 0.031). For the HM patients, OA3 patients compared with OK3 patients, axial length was significantly shorter in the OA3 group (25.78 ± 1.46 mm) than in the OK3 group (25.93 ± 1.94 mm) (p = 0.021); similarly, it was shorter in the OA4 patients (25.86 ± 1.21 mm) than in the OK4 patients (26.05 ± 1.57 mm) (p = 0.011). Combined treatment with atropine and OK lenses would be a choice of treatment to control the development of myopia.
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影响因子：
4.6
作者：
Jiang X;Kurihara T;Kunimi H;Miyauchi M;Ikeda SI;Mori K;Tsubota K;Torii H;Tsubota K
通讯作者：
Tsubota K
影响因子：
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通讯作者：
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通讯作者：
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影响因子：
4.4
作者：
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通讯作者：
Cheung, Sin-Wan