Cyclosporin-A ameliorated interstitial pneumonitis in a patient with amyopathic dermatomyositis
Cyclosporin-A ameliorated interstitial pneumonitis in a patient with amyopathic dermatomyositis
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环孢素 A 可改善无肌病性皮肌炎患者的间质性肺炎
DOI：
10.3109/s101650200061
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发表时间：
2002
影响因子：
2.2
通讯作者：
Takashi Horie
中科院分区：
文献类型：
--
作者：
Masanori Aoki;Yoshihiro Matsukawa;Motohide Kaneko;Tomohiro Hattori;Takako Shimizu;Susumu Nishinarita;Takashi Horie
摘要一位40岁女性无肌病性皮肌炎（ADM）发展为急性肺炎。 尽管甲基强的松龙冲击治疗，肺炎恶化。因此，我们开始环孢菌素A（Cy-A）治疗成功，但发生了卡氏肺孢子虫（PC）肺炎。通过胸部X线检查、KL-6和PC聚合酶链反应（PCR）诊断皮肌炎（DM）相关性肺炎和PC肺炎并存。因此，我们继续Cy-A治疗，以改善肺炎。Cy-A似乎对DM患者的皮质类固醇耐药性肺炎有效。
Abstract A 40-year-old woman with amyopathic dermatomyositis (ADM) developed acute pneumonitis. Despite pulse methylprednisolone therapy, the pneumonitis worsened. We therefore initiated cyclosporin-A (Cy-A) therapy with success, although Pneumocystis carinii (PC) pneumonia occurred. Coexistence of dermatomyositis (DM)-related pneumonitis and PC pneumonia was diagnosed by means of chest X-ray findings, KL-6, and polymerase chain reaction (PCR) for PC. We thus continued Cy-A therapy to ameliorate the pneumonitis. Cy-A appeared to be effective for corticosteroid-resistant pneumonitis in a patient with DM.
影响因子：
6.5
作者：
EUWER, RL;SONTHEIMER, RD
通讯作者：
SONTHEIMER, RD