Functional brown adipose tissue is related to muscle volume in children and adolescents.
Functional brown adipose tissue is related to muscle volume in children and adolescents.
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功能性棕色脂肪组织与儿童和青少年的肌肉体积有关。
DOI：
10.1016/j.jpeds.2010.11.020
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发表时间：
2011-05
影响因子：
5.1
通讯作者：
Hu, Houchun H.
中科院分区：
文献类型：
--
作者：
Gilsanz, Vicente;Chung, Sandra A.;Jackson, Hollie;Dorey, Frederick J.;Hu, Houchun H.
我们研究了儿童患者正电子发射断层扫描/计算机断层扫描(PET/CT)对棕色脂肪组织(BAT)的描述是否与人体测量学测量有关。我们对71名接受PET/CT检查的儿童和青少年进行了体重、肥胖和肌肉组织的测量，并比较了有无BAT的患者。我们使用回归分析来评估BAT和人体测量之间的关系。共有30名患者(42%)在PET/CT上显示BAT，26名女孩中有10名(38%)，45名男孩中有20名(44%)。与无功能性BAT的患者相比，BAT患者的颈部肌肉(1880±908 cm~3比1299±806 cm~3；P=0.028；男孩1295±586 cm~3比854±392 cm~3；P=.030)和臀肌肌肉(1359±373 cm~3比1061±500 cm~3；P=0.032男孩1138±425 cm~3比827±297 cm~3；P=0.038)，但在年龄、体重指数或皮下脂肪测量方面没有差异。通过Logistic回归分析，颈部和盆腔肌肉结构独立于年龄、性别、体型和扫描季节预测BAT的存在(分别为P=0.018和0.009)。在PET/CT检查中可见BAT的儿童患者的肌肉体积明显大于未显示BAT的患者。
We examined whether the depiction of brown adipose tissue (BAT) with positron emission tomography/computed tomography (PET/CT) in pediatric patients is associated with anthropometric meaures. We determined measures of body mass, adiposity, and musculature in 71 children and adolescents who underwent PET/CT examinations and compared patients with and without BAT. We used regression analyses to assess the relation between BAT and anthropometric measures. A total of 30 patients (42%) had BAT depicted on PET/CT, 10 of 26 girls (38%) and 20 of 45 boys (44%). Compared with patients without functional BAT, patients with BAT had significantly greater neck musculature (1880 ± 908 cm3 versus 1299 ± 806 cm3; P = .028 for boys and 1295 ± 586 cm3 versus 854 ± 392 cm3; P = .030 for girls) and gluteus musculature (1359 ± 373 cm3 versus 1061 ± 500 cm3; P = .032 for boys and 1138 ± 425 cm3 versus 827 ± 297 cm3; P = .038 for girls), but no differences in age, body mass index, or measures of subcutaneous fat. With logistic regression analyses, neck and pelvic musculature predicted the presence of BAT independently of age, sex, body size, and season of scan (P = .018 and .009, respectively). Pediatric patients with visualized BAT on PET/CT examinations had significantly greater muscle volume than patients with no visualized BAT.
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影响因子：
7.7
作者：
Saito M;Okamatsu-Ogura Y;Matsushita M;Watanabe K;Yoneshiro T;Nio-Kobayashi J;Iwanaga T;Miyagawa M;Kameya T;Nakada K;Kawai Y;Tsujisaki M
通讯作者：
Tsujisaki M
影响因子：
4.4
作者：
Hu, Houchun H.;Smith, Daniel L., Jr.;Nayak, Krishna S.;Goran, Michael I.;Nagy, Tim R.
通讯作者：
Nagy, Tim R.
DOI：
10.1007/s00259-006-0253-9
发表时间：
2007-05-01
影响因子：
9.1
作者：
Bar-Sever, Zvi;Keidar, Zohar;Israel, Ora
通讯作者：
Israel, Ora
影响因子：
4.8
作者：
Hamann, A;Flier, JS;Lowell, BB
通讯作者：
Lowell, BB
影响因子：
4.8
作者：
Petrovic, Natasa;Walden, Tomas B.;Nedergaard, Jan
通讯作者：
Nedergaard, Jan