Warts and all: human papillomavirus in primary immunodeficiencies.
Warts and all: human papillomavirus in primary immunodeficiencies.
复制标题
DOI：
10.1016/j.jaci.2012.07.049
复制
发表时间：
2012-11
影响因子：
14.2
通讯作者：
Holland, Steven M.
中科院分区：
文献类型：
--
作者：
Leiding, Jennifer W.;Holland, Steven M.
人类乳头瘤病毒(HPV)感染几乎是普遍的，并最终没有症状，但HPV的病理性感染是严重的、反复发作的，并且对治疗难以治疗。它也是一种被低估的原发免疫缺陷的表现。Ever1、EveR2、GATA2、CXCR4和DOCK8的突变通常与广泛的HPV感染有关，而其他几种原发免疫缺陷患严重HPV的频率要低得多。我们回顾了严重HPV感染的免疫缺陷及其背后的机制。
Infection with human papilloma virus (HPV) is almost universal and eventually asymptomatic, but pathologic infection with HPV is severe, recurrent, and recalcitrant to therapy. It is also an underappreciated manifestation of primary immunodeficiency. Mutations in EVER1, EVER2, GATA2, CXCR4, and DOCK8 are typically associated with extensive HPV infections, whereas several other primary immune defects have severe HPV much less frequently. We review immunodeficiencies with severe HPV infections and the mechanisms underlying them.
登录
查看更多内容
影响因子：
158.5
作者：
CARBONARI, M;CHERCHI, M;FIORILLI, M
通讯作者：
FIORILLI, M
影响因子：
14.2
作者：
Al Khatib, Shadi;Keles, Sevgi;Garcia-Lioret, Maria;Koc-Aydiner, Elif Kara;Reisli, Ismail;Artac, Hasibe;Camcioglu, Yildiz;Cokugras, Haluk;Somer, Ayper;Kutukculer, Necil;Yilmaz, Mustafa;Ikinciogullari, Aydan;Yegin, Olcay;Yuksek, Mutlu;Genel, Ferah;Kucukosmanoglu, Ercan;Baki, Ali;Bahceciler, Nerin N.;Rambhatla, Anupama;Nickerson, Derek W.;McGhee, Sean;Barlan, Isil B.;Chatila, Talal
通讯作者：
Chatila, Talal
影响因子：
6.4
作者：
Carter, JJ;Koutsky, LA;Galloway, DA
通讯作者：
Galloway, DA
影响因子：
2.8
作者：
Bouma, Gerben;Burns, Siobhan O.;Thrasher, Adrian J.
通讯作者：
Thrasher, Adrian J.
影响因子：
1.6
作者：
Akha, AAS;Humphrey, RL;Lederman, HM
通讯作者：
Lederman, HM