Moving Forward: Recent Developments for the Ferret Biomedical Research Model.

Moving Forward: Recent Developments for the Ferret Biomedical Research Model.
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DOI:
10.1128/mbio.01113-18
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发表时间:
2018-07-17
期刊:
影响因子:
6.4
通讯作者:
Schultz-Cherry S
Schultz-Cherry S
中科院分区:
生物学1区
文献类型:
--
作者:
Albrecht RA;Liu WC;Sant AJ;Tompkins SM;Pekosz A;Meliopoulos V;Cherry S;Thomas PG;Schultz-Cherry S

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自 1911 年首次报道以来,家养雪貂已成为无价的生物医学研究模型。虽然雪貂在流感病毒研究中的实用性得到广泛认可,但由于它们与人类共有的解剖、代谢和生理特征以及对许多人类病原体的易感性,雪貂被用于各种传染性和非传染性疾病模型。自 1911 年首次报道以来,家养雪貂已成为无价的生物医学研究模型。虽然雪貂在流感病毒研究中的实用性得到广泛认可,但由于它们与人类共有的解剖、代谢和生理特征以及对许多人类病原体的易感性,雪貂被用于各种传染性和非传染性疾病模型。然而,为了科学界的最大效用,必须克服该模型的局限性。在这里,我们描述了近期的重要进展,这些进展将加速这种动物模型的生物医学研究。
Since the initial report in 1911, the domestic ferret has become an invaluable biomedical research model. While widely recognized for its utility in influenza virus research, ferrets are used for a variety of infectious and noninfectious disease models due to the anatomical, metabolic, and physiological features they share with humans and their susceptibility to many human pathogens. Since the initial report in 1911, the domestic ferret has become an invaluable biomedical research model. While widely recognized for its utility in influenza virus research, ferrets are used for a variety of infectious and noninfectious disease models due to the anatomical, metabolic, and physiological features they share with humans and their susceptibility to many human pathogens. However, there are limitations to the model that must be overcome for maximal utility for the scientific community. Here, we describe important recent advances that will accelerate biomedical research with this animal model.
DOI: 10.1084/jem.148.3.674
发表时间: 1978-09-01
期刊: The Journal of experimental medicine
影响因子: --
作者:
Thormar H;Mehta PD;Brown HR
通讯作者: Brown HR